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1. (WO2016182882) NITROFURAN DERIVATIVES THAT INDUCE APOPTOSIS IN BREAST CANCER CELLS BY ACTIVATING PROTEIN EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/182882    International Application No.:    PCT/US2016/031121
Publication Date: 17.11.2016 International Filing Date: 06.05.2016
IPC:
C07D 403/14 (2006.01), A61K 31/517 (2006.01)
Applicants: OKLAHOMA MEDICAL RESEARCH FOUNDATION [US/US]; 825 N.E. 13th Street Oklahoma City, OK 73104 (US)
Inventors: WANG, Weidong; (US)
Agent: CHALKER, Daniel J.; (US)
Priority Data:
62/158,924 08.05.2015 US
Title (EN) NITROFURAN DERIVATIVES THAT INDUCE APOPTOSIS IN BREAST CANCER CELLS BY ACTIVATING PROTEIN EXPRESSION
(FR) DÉRIVÉS DE NITROFURANE QUI INDUISENT L'APOPTOSE DANS LES CELLULES DU CANCER DU SEIN PAR ACTIVATION DE L'EXPRESSION DE PROTÉINES
Abstract: front page image
(EN)The present invention provides 5-nitrofuran-2-amide derivatives and methods of using the same in the treatment of cancer and induction of apoptosis by activating C/EBP-homologous protein expression.
(FR)La présente invention concerne des dérivés de 5-nitrofuran-2-amide et des procédés d'utilisation de ceux-ci dans le traitement du cancer et d'induction de l'apoptose par activation de l'expression d'une protéine C/EBP homologue .
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)