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1. (WO2016180034) ANTI-CTLA-4 AND ANTI-PD-1 DUAL VARIABLE DOMAIN IMMUNOGLOBULIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/180034    International Application No.:    PCT/CN2016/000226
Publication Date: 17.11.2016 International Filing Date: 26.04.2016
IPC:
C07K 16/46 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01)
Applicants: HU, Pinliang [CN/CN]; (CN).
HE, Yun [CN/CN]; (CN).
BAI, Jie [CN/CN]; (CN).
HONG, Weidong [CN/CN]; (CN).
ZOU, Jing [CN/CN]; (CN).
SONG, Lingyun [CN/CN]; (CN).
YANG, Zerong [CN/CN]; (CN)
Inventors: HU, Pinliang; (CN).
HE, Yun; (CN).
BAI, Jie; (CN).
HONG, Weidong; (CN).
ZOU, Jing; (CN).
SONG, Lingyun; (CN).
YANG, Zerong; (CN)
Priority Data:
201510240134.5 13.05.2015 CN
Title (EN) ANTI-CTLA-4 AND ANTI-PD-1 DUAL VARIABLE DOMAIN IMMUNOGLOBULIN
(FR) IMMUNOGLOBULINE À DOMAINE VARIABLE DOUBLE ANTI-CTLA -4 ET ANTI-PD -1
(ZH) 抗CTLA-4和PD-1的双重可变结构域免疫球蛋白
Abstract: front page image
(EN)Disclosed is a dual variable domain immunoglobulin (DVD-Ig) specifically binding to PD-1 and/or CTLA-4, and use thereof in the preparation of drugs for treating tumours.
(FR)L'invention concerne une immunoglobuline à domaine variable double (DVD-Ig) qui se lie de manière spécifique à PD -1 et/ou CTLA -4, et l'utilisation de celle-ci dans la préparation de médicaments pour le traitement de tumeurs.
(ZH)公开了一种特异结合PD-1和/或CTLA-4的双重可变结构域免疫球蛋白及其在制备治疗肿瘤的药物中的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)