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1. (WO2016179417) EXOSOME DELIVERY OF MICRORNAS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/179417    International Application No.:    PCT/US2016/031031
Publication Date: 10.11.2016 International Filing Date: 05.05.2016
IPC:
A61K 38/00 (2006.01), A61K 38/18 (2006.01), A61K 38/48 (2006.01), C12N 15/88 (2006.01)
Applicants: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION [US/US]; 615 Arapeen Drive Suite 310 Salt Lake City, Utah 84108 (US)
Inventors: O'CONNELL, Ryan; (US).
ALEXANDER, Margaret; (US)
Agent: HULSE, Loren R.; (US)
Priority Data:
62/157,875 06.05.2015 US
Title (EN) EXOSOME DELIVERY OF MICRORNAS
(FR) ADMINISTRATION D'EXOSOMES DE MICRO-ARN
Abstract: front page image
(EN)A method of repressing a target messenger RNA (mRNA) in a subject is provided. The method may include the step of loading exosomes with a microRNA (miRNA), wherein the miRNA is configured to repress the target mRNA. The method may further include the step of introducing the one or more miRNA-loaded exosomes into the subject.
(FR)Un procédé de répression d'une cible ARN messager (arnm) chez un sujet. Le procédé peut comprendre l'étape de chargement des exosomes avec un microARN (miARN), dans lequel l'arnmi est configuré pour réprimer l'arnm cible. Le procédé peut en outre comprendre l'étape consistant à introduire un ou plusieurs arnmi-chargé des exosomes dans le sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)