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1. (WO2016179415) SOLID FORMS OF A COMPOUND MODULATING KINASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/179415    International Application No.:    PCT/US2016/031027
Publication Date: 10.11.2016 International Filing Date: 05.05.2016
IPC:
C07D 471/04 (2006.01), A61K 31/437 (2006.01), A61P 35/00 (2006.01)
Applicants: PLEXXIKON INC. [US/US]; 91 Bolivar Drive, Suite A Berkeley, CA 94710 (US)
Inventors: IBRAHIM, Prabha, N.; (US).
VISOR, Gary, Conrad; (US)
Agent: TANNER, Lorna, L.; (US)
Priority Data:
62/157,902 06.05.2015 US
Title (EN) SOLID FORMS OF A COMPOUND MODULATING KINASES
(FR) FORMES SOLIDES D'UN COMPOSÉ MODULANT LES KINASES
Abstract: front page image
(EN)Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]- (6-trifluoromethyl-pyridin-3-ylmethyl)-amine HC1 salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized. Also provided are methods of using the solid forms.
(FR)L'invention concerne des formes solides du composé sel HCl de [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylméthyl)-pyridin-2-yl]-(6-trifluorométhyl-pyridin-3-ylméthyl)-amine (composé I), et sa base libre, actives sur les protéines kinases récepteurs c-Kit et/ou c-Fms et/ou Flt3, préparées et caractérisées. L'invention concerne également des procédés d'utilisation de ces formes solides.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)