WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016179398) ISOFORM-SELECTIVE LYSINE DEACETYLASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/179398    International Application No.:    PCT/US2016/030995
Publication Date: 10.11.2016 International Filing Date: 05.05.2016
IPC:
C07K 5/12 (2006.01), A61K 38/12 (2006.01), A61P 35/00 (2006.01), A61P 25/28 (2006.01), A61P 11/06 (2006.01), A61P 9/00 (2006.01), A61P 31/18 (2006.01), A61P 37/06 (2006.01)
Applicants: WASHINGTON UNIVERSITY [US/US]; One Brookings Drive St. Louis, Missouri 63130 (US)
Inventors: MARSHALL, Garland, R.; (US).
KYEI, George,B.; (US).
ONKEN, Michael, D.; (US).
RATNER, Lee; (US).
REDDY, Nandarapu, Damodara; (US)
Agent: TIETZ, Paul, D.; (US)
Priority Data:
62/156,986 05.05.2015 US
Title (EN) ISOFORM-SELECTIVE LYSINE DEACETYLASE INHIBITORS
(FR) INHIBITEURS DE LYSINE DÉSACÉTYLASE SÉLECTIFS ENVERS LES ISOFORMES
Abstract: front page image
(EN)Isoform-selective lysine deacetylase inhibitors are described. Inhibitors of the lysine deacetylase enzyme are useful as antitumor drugs and for treating addiction, asthma, cardio-vascular disease, immunosuppression, neurodegenerative diseases, sepsis, sickle-cell disease, uveal melanoma and termination of viral latency, particularly HIV-1 latency.
(FR)La présente invention concerne des inhibiteurs de lysine désacétylase sélectifs envers les isoformes. Des inhibiteurs de l'enzyme lysine désacétylase sont utiles en tant que médicaments antitumoraux et pour le traitement de la dépendance, de l'asthme, de la maladie cardio-vasculaire, de l'immunosuppression, de maladies neurodégénératives, de la septicémie, de la drépanocytose, du mélanome choroïdien et de la fin de la latence virale, en particulier la latence du VIH-1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)