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1. (WO2016179247) PROCESS TO EXTRACT AND PURIFY DELTA-9-TETRAHYDROCANNABINOL
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2016/179247 International Application No.: PCT/US2016/030719
Publication Date: 10.11.2016 International Filing Date: 04.05.2016
IPC:
A61K 31/35 (2006.01) ,A61K 31/352 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
Applicants:
AXIM BIOTECHNOLOGIES, INC. [US/US]; 18 East 50th Street, 5th Floor New York, New York 10022, US
Inventors:
CHANGOER, Lekhram; NL
VAN DER LOO, Cornelis Herman Michel; NL
KELLER, Erik; NL
Agent:
GLATZEL, Khanh; US
Priority Data:
62/158,07507.05.2015US
Title (EN) PROCESS TO EXTRACT AND PURIFY DELTA-9-TETRAHYDROCANNABINOL
(FR) PROCÉDÉ D'EXTRACTION ET DE PURIFICATION DE DELTA-9-TÉTRAHYDROCANNABINOL
Abstract:
(EN) Δ9-THC acid is extracted from cannabis flowers using a first organic solvent, then separated using a second aqueous solvent. Δ9-THC acid is converted to Δ9-THC carboxylic salt before being extracted by a third organic solvent and converted back to Δ9-THC carboxylic acid. Using a solvent swap, Δ9-THC carboxylic acid is decarboxylated and extracted again with an organic solvent prior to purification to give Δ9-THC.
(FR) L'invention concerne un acide Δ9-THC carboxylique extrait de fleurs de cannabis à l'aide d'un premier solvant organique, puis séparé à l'aide d'un deuxième solvant aqueux. L'acide Δ9-THC est transformé en sel Δ9-THC carboxylique avant d'être extrait par un troisième solvant organique et transformé de nouveau en acide Δ9-THC carboxylique. À l'aide d'un échange de solvant, l'acide Δ9-THC carboxylique est décarboxylé et à nouveau extrait avec un solvant organique avant de procéder à une purification pour donner Δ9-THC.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3291806