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1. (WO2016179212) ANTIBODY THERAPEUTICS AGAINST FILOVIRUS INFECTIONS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/179212    International Application No.:    PCT/US2016/030652
Publication Date: 10.11.2016 International Filing Date: 04.05.2016
IPC:
A61K 39/00 (2006.01), A61K 39/395 (2006.01), A61K 39/42 (2006.01), C07K 16/10 (2006.01), C07K 16/46 (2006.01)
Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. [US/US]; 1300 Morris Park Avenue Bronx, NY 10461 (US)
Inventors: CHANDRAN, Kartik; (US).
WEC, Anna, Z.; (US).
NYAKATURA, Elisabeth, K.; (US).
LAI, Jonathan, R.; (US)
Agent: MILLER, Alan, D.; (US)
Priority Data:
62/157,104 05.05.2015 US
Title (EN) ANTIBODY THERAPEUTICS AGAINST FILOVIRUS INFECTIONS AND USES THEREOF
(FR) AGENTS THÉRAPEUTIQUES À BASE D'ANTICORPS DIRIGÉS CONTRE DES INFECTIONS PAR FILOVIRUS ET LEURS UTILISATIONS
Abstract: front page image
(EN)Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick CI (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.
(FR)L'invention concerne des anticorps bispécifiques et des constructions de fusion bispécifiques qui se lient au récepteur Niemann-Pick CI (NPC1) pour traiter ou prévenir des infections par filovirus, des compositions pharmaceutiques comprenant les anticorps bispécifiques, et des méthodes thérapeutiques utilisant les anticorps bispécifiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)