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1. (WO2016178162) SYNTHESIS OF INTERMEDIATES USED IN THE MANUFACTURE OF ANTI-HIV AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/178162    International Application No.:    PCT/IB2016/052548
Publication Date: 10.11.2016 International Filing Date: 04.05.2016
IPC:
C07D 473/34 (2006.01), C07F 9/6561 (2006.01)
Applicants: CBZ INVESTMENTS LTD. [--/GB]; 122, Feering Hill, Feering, Colchester, Essex CO5 9PY (GB)
Inventors: PRADHAN, Braja Sundar; (IN).
AMARNATH, Kommireddy; (IN).
VEMPALA, Naresh; (IN).
RAHMAN, Md. Ataur; (IN)
Priority Data:
1786/MUM/2015 05.05.2015 IN
Title (EN) SYNTHESIS OF INTERMEDIATES USED IN THE MANUFACTURE OF ANTI-HIV AGENTS
(FR) SYNTHÈSE D'INTERMÉDIAIRES UTILISÉS DANS LA FABRICATION D'AGENTS ANTI-VIH
Abstract: front page image
(EN)The present invention relates to a process of preparing intermediates of Formula (I). The process comprises of reacting compound of Formula (III) with compound of Formula (V) in the presence of a solvent selected from an alcohol, ether or water to form compound of Formula (I) wherein, R1 is selected from –NH2, Cl, Br, NHCOR", wherein R" is alkyl, aryl, Schiff's base of formula N=CHR', wherein R' is alkyl or aryl; R2 is selected from H, alkyl; R3 and R4, each independently is H; R5 and R6, each independently is H, alkyl; R7 is H, alkyl; and R8 is H, alkyl.
(FR)La présente invention concerne un procédé de préparation d'intermédiaires de Formule (I). Le procédé comprend la réaction du composé de formule (III) avec le composé de formule (V) en présence d'un solvant choisi parmi un alcool, un éther ou de l'eau pour former un composé de formule (I) dans laquelle R1 est choisi parmi –NH2, Cl, Br, NHCOR ", où R" est un groupe alkyle, aryle, une base de Schiff de formule N=CHR ', où R'est un groupe alkyle ou aryle ; R2 est choisi parmi H, alkyle ; R3 et R4 sont chacun indépendamment H ; R5 et R6 sont chacun indépendamment H, alkyle ; R7 est H, alkyle ; et R8 est H, alkyle.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)