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Machine translation
1. (WO2016176583) MODULATION OF IMMUNE RESPONSE USING BTLA AGONIST ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/176583    International Application No.:    PCT/US2016/030138
Publication Date: 03.11.2016 International Filing Date: 29.04.2016
IPC:
A61K 39/395 (2006.01)
Applicants: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE [US/US]; 10901 North Torrey Pines Road La Jolla, CA 92037 (US)
Inventors: WARE, Carl, F.; (US).
SEDY, John; (US).
NORRIS, Paula; (US)
Agent: HAILE, Lisa, A.; (US)
Priority Data:
62/154,484 29.04.2015 US
Title (EN) MODULATION OF IMMUNE RESPONSE USING BTLA AGONIST ANTIBODIES
(FR) MODULATION DE RÉPONSE IMMUNITAIRE AU MOYEN D'ANTICORPS AGONISTES DE BTLA
Abstract: front page image
(EN)The present invention relates to the seminal discovery that BTLA agonist antibodies modulate the immune system. Specifically, the present invention provides antibodies which bind BTLA in the activated state enhancing BTLA signaling. The present invention further provides methods of treating immune and inflammatory diseases and disorders with a BTLA agonist antibody.
(FR)La présente invention concerne la découverte fondamentale qui a été faite selon laquelle des anticorps agonistes de BTLA modulent le système immunitaire. Spécifiquement, la présente invention concerne des anticorps qui se lient à BTLA à l'état activé permettant d'améliorer la signalisation de BTLA. La présente invention concerne en outre des procédés de traitement de maladies et de troubles immunitaires et inflammatoires avec un anticorps agoniste de BTLA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)