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1. (WO2016176437) TARGETING NAD+ TO TREAT CHEMOTHERAPY AND RADIOTHERAPY INDUCED COGNITIVE IMPAIRMENT, NEUROPATHIES AND INACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/176437    International Application No.:    PCT/US2016/029765
Publication Date: 03.11.2016 International Filing Date: 28.04.2016
IPC:
A61P 25/02 (2006.01), A61P 25/28 (2006.01), A61K 31/455 (2006.01), A61K 31/7084 (2006.01), A61K 38/45 (2006.01)
Applicants: NEWSOUTH INNOVATIONS PTY LIMITED [AU/AU]; Rupert Myers Bldg., Gate 14 Barker Street University Of New South Wales Sydney, New South Wales, 2052 (AU)
Inventors: WU, Lindsay; (AU).
SINCLAIR, David, A.; (US)
Agent: HALSTEAD, David, P.; (US)
Priority Data:
62/153,876 28.04.2015 US
Title (EN) TARGETING NAD+ TO TREAT CHEMOTHERAPY AND RADIOTHERAPY INDUCED COGNITIVE IMPAIRMENT, NEUROPATHIES AND INACTIVITY
(FR) CIBLAGE DE NAD+ POUR TRAITER LA DÉFICIENCE COGNITIVE, LES NEUROPATHIES ET L'INACTIVITÉ INDUITES PAR LA CHIMIOTHÉRAPIE ET LA RADIOTHÉRAPIE
Abstract: front page image
(EN)Methods and compositions for preventing or treating peripheral neuropathy, cognitive deficits, inactivity, depression, chemotherapy and/or radiotherapy induced peripheral neuropathy and cognitive deficits, and improving cognitive performance, in a subject in need thereof are disclosed. The disclosed methods include the step of administering to the subject an effective amount of an agent that increases the level of NAD+ in the subject.
(FR)La présente invention concerne des méthodes et des compositions pour prévenir ou traiter la neuropathie périphérique, les déficits cognitifs, l'inactivité, la dépression, la neuropathie périphérique et les déficits cognitifs induits par la chimiothérapie et/ou la radiothérapie, et améliorer les performances cognitives, chez un sujet qui en a besoin. Les méthodes selon l'invention comprennent l'étape consistant à administrer au sujet une quantité efficace d'un agent qui augmente le niveau de NAD+ chez le sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)