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1. (WO2016175228) PROPHYLACTIC AND THERAPEUTIC AGENT FOR COMPLICATIONS AFTER CATARACT SURGERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/175228    International Application No.:    PCT/JP2016/063149
Publication Date: 03.11.2016 International Filing Date: 27.04.2016
IPC:
A61K 31/551 (2006.01), A61P 27/02 (2006.01), A61P 43/00 (2006.01)
Applicants: HONJO Megumi [JP/JP]; (JP).
KOWA COMPANY, LTD. [JP/JP]; 6-29, Nishiki 3-chome, Naka-ku, Nagoya-shi, Aichi 4608625 (JP)
Inventors: HONJO Megumi; (JP).
OHTA Masayuki; (JP)
Agent: SAEKI, Norio; (JP)
Priority Data:
2015-089918 27.04.2015 JP
Title (EN) PROPHYLACTIC AND THERAPEUTIC AGENT FOR COMPLICATIONS AFTER CATARACT SURGERY
(FR) AGENT PROPHYLACTIQUE ET THÉRAPEUTIQUE POUR DES COMPLICATIONS SURVENANT APRÈS UNE CHIRURGIE DE LA CATARACTE
(JA) 白内障術後合併症の予防治療剤
Abstract: front page image
(EN)Provided is a novel drug for preventing and treating complications after cataract surgery such as secondary cataract and anterior capsular contraction occurring after cataract surgery. The prophylactic and therapeutic agent according to the present invention for complications after cataract surgery such as secondary cataract and anterior capsular contraction comprises, as an active ingredient, 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline (ripasudil), a salt thereof or a solvate of the same.
(FR)L'invention concerne un nouveau médicament destiné à la prévention et au traitement des complications survenant après une chirurgie de la cataracte, telles que la cataracte secondaire et la contraction capsulaire antérieure se produisant après une chirurgie de la cataracte. L'agent prophylactique et thérapeutique selon la présente invention pour des complications survenant après une chirurgie de la cataracte, telles que la cataracte secondaire et la contraction capsulaire antérieure, comprend, en tant que principe actif, de la 4-fluoro-5-{[(2S)-2-méthyl-1,4-diazépan-1-yl]sulfonyl}isoquinoléine (ripasudil), un sel correspondant ou un solvate correspondant.
(JA)本発明は、白内障手術の後に発症する後発白内障、前嚢収縮等の白内障術後合併症の予防・治療のための新規な医薬を提供する。 本発明は、4-フルオロ-5-{[(2S)-2-メチル-1,4-ジアゼパン-1-イル]スルホニル}イソキノリン(リパスジル)若しくはその塩、又はそれらの溶媒和物を有効成分とする後発白内障、前嚢収縮等の白内障術後合併症の予防治療剤に関する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)