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1. (WO2016174607) MICROFLUIDIC DEVICE AND RELATIVE METHOD FOR THE GENERATION AND/OR CULTURE AND/OR MATURATION OF THREE- DIMENSIONAL CELL AND/OR TISSUE CONSTRUCTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/174607    International Application No.:    PCT/IB2016/052410
Publication Date: 03.11.2016 International Filing Date: 28.04.2016
IPC:
C12M 3/00 (2006.01), C12M 3/06 (2006.01), C12M 1/00 (2006.01), C12M 1/12 (2006.01), C12M 1/42 (2006.01)
Applicants: POLITECNICO DI MILANO [IT/IT]; Piazza Leonardo da Vinci, 32 20133 Milano (IT).
FONDAZIONE CARIPLO [IT/IT]; Via D. Manin, 23 20121 Milano (IT)
Inventors: REDAELLI, Alberto; (IT).
RASPONI, Marco; (IT).
OCCHETTA, Paola; (IT)
Agent: CASCI, Tamara; (IT)
Priority Data:
102015000013538 29.04.2015 IT
Title (EN) MICROFLUIDIC DEVICE AND RELATIVE METHOD FOR THE GENERATION AND/OR CULTURE AND/OR MATURATION OF THREE- DIMENSIONAL CELL AND/OR TISSUE CONSTRUCTS
(FR) DISPOSITIF MICROFLUIDIQUE ET PROCÉDÉ CORRESPONDANT POUR LA GÉNÉRATION ET/OU LA CULTURE ET/OU LA MATURATION DE CONSTRUCTIONS CELLULAIRES ET/OU TISSULAIRES TRIDIMENSIONNELLES
Abstract: front page image
(EN)A microfluidic device and a method described, which are suitable for the controlled generation and/or culture and/or maturation of a three-dimensional cell and/or tissue construct comprising a culture chamber which comprises: confinement means that define at least one compartment suitable for containing a cellular matrix and at least one compartment suitable for containing a culture medium, the confinement means being hydrophobic and pervious to said culture medium; and at least one counter element; wherein said confinement means and the at least one counter element are reciprocally mobile between a resting position and a compression position of the cellular matrix.
(FR)L’invention concerne un dispositif microfluidique et un procédé, qui sont appropriés pour la génération et/ou la culture et/ou la maturation contrôlée d'une construction cellulaire et/ou tissulaire tridimensionnelle comprenant une chambre de culture qui comprend : un moyen de confinement qui délimite au moins un compartiment approprié pour contenir une matrice cellulaire et au moins un compartiment approprié pour contenir un milieu de culture, le moyen de confinement étant hydrophobe et perméable à ce milieu de culture ; et au moins un contre-élément ; ledit moyen de confinement et l'au moins un contre-élément étant réciproquement mobiles entre une position de repos et une position de compression de la matrice cellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Italian (IT)