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1. (WO2016168370) METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR ENDOCRINE SYSTEM CONDITIONS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2016/168370 International Application No.: PCT/US2016/027378
Publication Date: 20.10.2016 International Filing Date: 13.04.2016
IPC:
A61K 35/74 (2015.01) ,A61K 35/741 (2015.01) ,A61P 1/00 (2006.01) ,G06F 19/12 (2011.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
[IPC code unknown for A61K 35/741]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
12
for modelling or simulation in systems biology, e.g. probabilistic or dynamic models, gene-regulatory networks, protein interaction networks or metabolic networks
Applicants:
UBIOME, INC. [US/US]; 360 Langton Street, #301 San Francisco, CA 94103, US
Inventors:
APTE, Zachary; US
ALMONACID, Daniel; US
RICHMAN, Jessica; US
BEHBAHANI, Siavosh, Rezvan; US
Agent:
SCHOX, Jeffrey; US
Priority Data:
62/147,05814.04.2015US
62/147,10714.04.2015US
62/147,20214.04.2015US
62/147,22614.04.2015US
62/147,30414.04.2015US
62/147,34814.04.2015US
62/147,35514.04.2015US
Title (EN) METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR ENDOCRINE SYSTEM CONDITIONS
(FR) PROCÉDÉ ET SYSTÈME DE DIAGNOSTICS ET DE TRAITEMENTS DÉRIVÉS DU MICROBIOME POUR DES DYSFONCTIONNEMENTS DU SYSTÈME ENDOCRINIEN
Abstract:
(EN) A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
(FR) L'invention concerne un procédé de caractérisation et/ou de diagnostic et/ou de traitement d'un dysfonctionnement du système endocrinien chez au moins un patient, le procédé comprenant les étapes consistant : à recevoir un ensemble agrégé d'échantillons biologiques provenant d'une population de patients ; à générer au moins un ensemble de données sur la composition du microbiome et/ou un ensemble de données sur la diversité fonctionnelle du microbiome pour la population de patients ; à caractériser le dysfonctionnement du système endocrinien sur la base de caractéristiques extraites de l'ensemble de données sur la composition du microbiome et/ou de l'ensemble de données sur la diversité fonctionnelle du microbiome ; générer, sur la base de cette caractérisation, un modèle thérapeutique conçu pour corriger le dysfonctionnement du système endocrinien ; et promouvoir auprès du sujet, sur un dispositif de sortie qui lui est associé, un traitement sur la base de la caractérisation et du modèle thérapeutique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)