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1. (WO2016168316) METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR NEUROLOGICAL HEALTH ISSUES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2016/168316 International Application No.: PCT/US2016/027312
Publication Date: 20.10.2016 International Filing Date: 13.04.2016
IPC:
C12Q 1/68 (2006.01) ,A61K 35/74 (2015.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
Applicants:
UBIOME, INC. [US/US]; 360 Langton Street, #301 San Francisco, CA 94103, US
Inventors:
APTE, Zachary; US
ALMONACID, Daniel; US
RICHMAN, Jessica; US
BEHBAHANI, Siavosh, Rezvan; US
Agent:
SCHOX, Jeffrey; US
Priority Data:
62/146,81013.04.2015US
62/146,83313.04.2015US
62/146,85213.04.2015US
62/147,05814.04.2015US
62/147,07714.04.2015US
62/147,12414.04.2015US
62/147,31514.04.2015US
62/147,33714.04.2015US
Title (EN) METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR NEUROLOGICAL HEALTH ISSUES
(FR) MÉTHODE ET SYSTÈME DE DIAGNOSTIC DÉRIVÉ DU MICROBIOME ET DE TRAITEMENT DE PROBLÈMES THÉRAPEUTIQUES DESTINÉS À DES PROBLÈMES DE SANTÉ NEUROLOGIQUES
Abstract:
(EN) A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
(FR) L'invention concerne une méthode pour au moins caractériser, diagnostiquer et traiter un problème de santé neurologique chez au moins un sujet, la méthode comprenant les étapes consistant à : recevoir un ensemble agrégé d'échantillons biologiques provenant d'une population de sujets; générer au moins un ensemble de données sur la composition du microbiome et/ou un ensemble de données concernant la diversité fonctionnelle du microbiome pour la population de sujets; générer une caractérisation du problème de santé neurologique en fonction des caractéristiques extraites d'au moins l'un parmi l'ensemble de données sur la composition du microbiome et l'ensemble de données sur la diversité fonctionnelle du microbiome; en fonction de la caractérisation, générer un modèle thérapeutique configuré pour corriger le problème de santé neurologique; et au niveau d'un dispositif de sortie associé au sujet, préconiser une thérapie au sujet basée sur la caractérisation et le modèle thérapeutique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)