Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Saturday 31.10.2020 at 7:00 AM CET
Settings

Settings

Goto Application

1. WO2016153741 - MULTI-SPECTRAL LASER IMAGING (MSLI) METHODS AND SYSTEMS FOR BLOOD FLOW AND PERFUSION IMAGING AND QUANTIFICATION

Publication Number WO/2016/153741
Publication Date 29.09.2016
International Application No. PCT/US2016/020201
International Filing Date 01.03.2016
IPC
G01N 21/359 2014.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
35using infra-red light
359using near infra-red light
G01N 33/49 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
49blood
CPC
A61B 2576/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2576Medical imaging apparatus involving image processing or analysis
A61B 5/0035
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
0035adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
A61B 5/0077
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
A61B 5/0261
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
026Measuring blood flow
0261using optical means, e.g. infra-red light
A61B 5/7207
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7203for noise prevention, reduction or removal
7207of noise induced by motion artifacts
A61B 5/721
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7203for noise prevention, reduction or removal
7207of noise induced by motion artifacts
721using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
Applicants
  • EAST CAROLINA UNIVERSITY [US]/[US]
Inventors
  • CHEN, Cheng
  • FERGUSON, T. Bruce, Jr.
  • PENG, Zhiyong
  • JACOBS, Kenneth Michael
Agents
  • MYERS BIGEL & SIBLEY, P.A.
Priority Data
15/054,83026.02.2016US
62/136,01020.03.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTI-SPECTRAL LASER IMAGING (MSLI) METHODS AND SYSTEMS FOR BLOOD FLOW AND PERFUSION IMAGING AND QUANTIFICATION
(FR) PROCÉDÉS ET SYSTÈMES D'IMAGERIE LASER MULTISPECTRALE (MSLI) PERMETTANT UNE IMAGERIE ET UNE QUANTIFICATION D'UNE PERFUSION SANGUINE ET D'UN FLUX SANGUIN
Abstract
(EN)
Some embodiments of the present inventive concept provide a system that uses two wavelengths of differential transmittance through a sample to apply laser speckle or laser Doppler imaging. A first of the two wavelengths is within the visible range that has zero or very shallow penetration. This wavelength captures the anatomical structure of tissue/organ surface and serves as a position marker of the sample but not the subsurface movement of blood flow and perfusion. A second wavelength is in the near Infra-Red (NIR) range, which has much deeper penetration. This wavelength reveals the underlying blood flow physiology and correlates both to the motion of the sample and also the movement of blood flow and perfusion. Thus, true motion of blood flow and perfusion can be derived from the NIR imaging measurement without being affected by the motion artifact of the target.
(FR)
La présente invention porte, dans certains modes de réalisation du concept, sur un système qui utilise deux longueurs d'onde de transmittance différentielle à travers un échantillon pour appliquer une imagerie laser Doppler ou à granularité laser. Une première des deux longueurs d'onde se situe dans la plage visible ne contenant aucune pénétration ou une pénétration très peu profonde. Cette longueur d'onde capture la structure anatomique de la surface du tissu/de l'organe et fait office de marqueur de position de l'échantillon mais pas du mouvement de subsurface du flux sanguin et de la perfusion sanguine. Une seconde longueur d'onde se situe dans la plage du proche infrarouge (NIR pour Near Infra-Red), qui présente une pénétration beaucoup plus profonde. Cette longueur d'onde révèle la physiologique sous-jacente du flux sanguin et est en corrélation à la fois avec le mouvement de l'échantillon et également avec le mouvement du flux sanguin et de la perfusion sanguine. Ainsi, un mouvement vrai du flux sanguin et de la perfusion sanguine peut être tiré de la mesure d'imagerie proche infrarouge sans être affecté par l'artefact de mouvement de la cible.
Latest bibliographic data on file with the International Bureau