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1. WO2016153185 - ANTICANCER FUNCTIONAL PEPTIDE FOR INHIBITING PROLIFERATION OF CANCER STEM CELL, AND USE THEREOF

Publication Number WO/2016/153185
Publication Date 29.09.2016
International Application No. PCT/KR2016/002109
International Filing Date 03.03.2016
IPC
A61K 38/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 47/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
CPC
A61K 38/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61K 47/30
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
A61K 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • 서울대학교산학협력단 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION [KR]/[KR]
  • 주식회사 나이벡 NANO INTELLIGENT BIOMEDICAL ENGINEERING CORPORATION CO. LTD [KR]/[KR]
Inventors
  • 박윤정 PARK, Yoon Jeong
  • 정종평 CHUNG, Chong-Pyoung
  • 이주연 LEE, Jue-Yeon
  • 서진숙 SUH, Jin Sook
Agents
  • 이처영 LEE, Cheo Young
Priority Data
10-2015-004270026.03.2015KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) ANTICANCER FUNCTIONAL PEPTIDE FOR INHIBITING PROLIFERATION OF CANCER STEM CELL, AND USE THEREOF
(FR) PEPTIDE FONCTIONNEL ANTICANCÉREUX DESTINÉ À INHIBER LA PROLIFÉRATION DE CELLULES SOUCHES CANCÉREUSES, ET SON UTILISATION
(KO) 암 줄기세포의 증식억제용 항암기능성 펩타이드 및 그 용도
Abstract
(EN)
The present invention relates to an antitumor composition comprising a peptide which induces proliferation inhibition and death of a cancer stem cell present in tumor tissue and, more specifically, to an anticancer functional peptide which inhibits activity of NF-kB specifically over-expressed in a cancer stem cell present in a tumor.
(FR)
La présente invention concerne une composition antitumorale comprenant un peptide qui induit l'inhibition de la prolifération et la mort d'une cellule souche cancéreuse présente dans un tissu tumoral et, plus spécifiquement, un peptide fonctionnel anticancéreux qui inhibe l'activité de NF-kB spécifiquement surexprimé dans une cellule souche cancéreuse présente dans une tumeur.
(KO)
본 발명은 종양조직내에 존재하는 암 줄기세포의 증식 억제 및 사멸을 유도하는 펩타이드를 포함하는 항종양 조성물에 관한 것으로, 보다 상세하게는 종양내에 존재하는 암 줄기세포에 특이적으로 과발현되어 있는 NF-κB의 활성을 저해하는 항암기능성 펩타이드에 관한 것이다.
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