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1. WO2016150449 - RECOMBINANT SOLUBLE HUMAN TISSUE FACTOR, METHOD OF ITS PRODUCTION AND USES THEREOF

Publication Number WO/2016/150449
Publication Date 29.09.2016
International Application No. PCT/DK2016/050090
International Filing Date 23.03.2016
IPC
C07K 14/745 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
745Blood coagulation or fibrinolysis factors
A61K 38/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
36Blood coagulation or fibrinolysis factors
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61L 24/043
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
043Mixtures of macromolecular materials
A61L 24/108
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
04containing macromolecular materials
10Polypeptides; Proteins
108Specific proteins or polypeptides not covered by groups A61L24/102 - A61L24/106
A61L 2400/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2400Materials characterised by their function or physical properties
04Materials for stopping bleeding
A61P 7/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
04Antihaemorrhagics; Procoagulants; Haemostatatic agents; Antifibrinolytic agents
Applicants
  • DANA GENETIC A/S [DK]/[DK]
Inventors
  • OSTHER, Kurt Bækgaard
Agents
  • PLOUGMANN VINGTOFT A/S
Priority Data
62/177,77623.03.2015US
62/285,35926.10.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) RECOMBINANT SOLUBLE HUMAN TISSUE FACTOR, METHOD OF ITS PRODUCTION AND USES THEREOF
(FR) FACTEUR TISSULAIRE HUMAIN SOLUBLE RECOMBINÉ, SON PROCÉDÉ DE PRODUCTION ET UTILISATIONS ASSOCIÉES
Abstract
(EN)
The present invention relates to a novel recombinant soluble human Tissue Factor(RshTF), which is an extrinsic hemostasis factor, produced in human HEK-cells. The present invention also relates to a hitherto unknown method of producing the RshTF as well as specific uses of RshTF and protein compositions comprising RshTF.
(FR)
La présente invention concerne un nouveau facteur tissulaire humain soluble recombiné (RshTF), qui est un facteur hémostatique extrinsèque, produit dans des cellules HEK humaines. La présente invention concerne également un procédé de production du RshTF, jusqu'à présent inconnu, ainsi que des utilisations spécifiques dudit RshTF et des compositions de protéines comprenant ledit RshTF.
Also published as
Latest bibliographic data on file with the International Bureau