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1. WO2016150379 - PHARMACEUTICAL COMPOSITION CONTAINING SILIBININ AND PUERARIA ROOT EXTRACT

Publication Number WO/2016/150379
Publication Date 29.09.2016
International Application No. PCT/CN2016/077038
International Filing Date 22.03.2016
IPC
A61K 36/82 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
82Theaceae (Tea family), e.g. camellia
A61K 36/488 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
488Pueraria (kudzu)
A61K 31/357 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
357having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A61K 47/24 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
24containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61P 1/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
CPC
A61K 2236/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2236Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
10Preparation or pretreatment of starting material
19involving fermentation using yeast, bacteria or both; enzymatic treatment
A61K 2236/33
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2236Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
30Extraction of the material
33involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
A61K 31/205
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
A61K 31/221
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
221with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
A61K 31/353
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 31/355
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
355Tocopherols, e.g. vitamin E
Applicants
  • 天士力制药集团股份有限公司 TASLY PHARMACEUTICAL GROUP CO., LTD. [CN]/[CN]
Inventors
  • 闫希军 YAN, Xijun
  • 吴迺峰 WU, Naifeng
  • 孙鹤 SUN, He
  • 闫凯境 YAN, Kaijing
  • 朱永宏 ZHU, Yonghong
  • 马晓慧 MA, Xiaohui
  • 章顺楠 ZHANG, Shunnan
  • 李长文 LI, Changwen
  • 白晓林 BAI, Xiaolin
  • 李婷 LI, Ting
  • 李磊 LI, Lei
  • 何毅 HE, Yi
Agents
  • 北京君尚知识产权代理事务所(普通合伙) BEIJING JOYSHINE INTELLECTUAL PROPERTY OFFICE
Priority Data
201510128638.823.03.2015CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION CONTAINING SILIBININ AND PUERARIA ROOT EXTRACT
(FR) COMPOSITION PHARMACEUTIQUE CONTENANT DE LA SILIBININE ET UN EXTRAIT DE RACINE DE PUERARIA
(ZH) 一种含有水飞蓟宾、葛根提取物的药物组合物
Abstract
(EN)
Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipin, 25-200 parts of Pu'er tea extract, and 5-50 parts of pueraria root extract.
(FR)
La présente invention concerne une composition pharmaceutique pour le traitement de la stéatose hépatique non alcoolique et son procédé de préparation. La composition est préparée à partir des médicaments en vrac suivants par rapport de poids : 8,75 à 60 parties de silibinine, 15 à 65 parties de phospholipine, 25 à 200 parties d'extrait de thé Pu'er, et 5-50 parties d'extrait de racine de pueraria.
(ZH)
一种治疗非酒精性脂肪肝的药物组合物及其制备方法,由下述重量比的原料药制成:水飞蓟宾8.75-60份,磷脂15-65份,普洱茶提取物25-200份,葛根提取物5-50份。
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