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1. WO2016146739 - AMYLIN ANALOGUES

Publication Number WO/2016/146739
Publication Date 22.09.2016
International Application No. PCT/EP2016/055793
International Filing Date 17.03.2016
Chapter 2 Demand Filed 21.09.2016
IPC
C07K 14/575 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 3/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • ZEALAND PHARMA A/S [DK]/[DK]
  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE]/[DE]
Inventors
  • JUST, Rasmus
  • DEMMER, Oliver
  • GIEHM, Lise
  • VILLADSEN, Jesper Sloth
  • MUNCH, Henrik Kofoed
  • SKARBALIENE, Jolanta
  • DERYABINA, Maria Alexandrovna
  • HAMPRECHT, Dieter Wolfgang
  • MATHIESEN, Jesper Mosolff
Agents
  • FORREST, Graham
Priority Data
15159737.418.03.2015EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AMYLIN ANALOGUES
(FR) ANALOGUES D'AMYLINE
Abstract
(EN)
The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes. The analogues have good physical and chemical stability, good solubility, and a long duration of action, and are well suited for use in the form of a liquid formulation.
(FR)
Cette invention concerne des analogues d'amyline et leur utilisation dans le traitement ou la prévention de diverses maladies, affections ou troubles, dont l'obésité, l'excès de prise alimentaire et les maladies métaboliques associées telles que le diabète. Les analogues ont une bonne stabilité physique et chimique, une bonne solubilité, et une longue durée d'action, et se prêtent à une utilisation sous la forme d'une formulation liquide.
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