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1. WO2016145974 - USE OF GENE ENGINEERING BACTERIA VPN 20009-M IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING CANCER METASTASIS

Publication Number WO/2016/145974
Publication Date 22.09.2016
International Application No. PCT/CN2016/074408
International Filing Date 24.02.2016
IPC
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C12N 1/21 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
21modified by introduction of foreign genetic material
C12N 15/74 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C12R 1/42 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1Microorganisms
01Bacteria or actinomycetales
42Salmonella
CPC
A61K 35/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61K 38/005
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
005Enzyme inhibitors
A61K 38/51
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
51Lyases (4)
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61K 48/005
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
005characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
A61P 35/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
Applicants
  • 南京华贞生物医药科技有限公司 NANJING SINOGEN BIOTECH & PHARMACEUTICAL INC. [CN]/[CN]
Inventors
  • 赵子建 ZHAO, Allanzijian
  • 周素瑾 ZHOU, Sujin
  • 林艳 LIN, Yan
  • 赵正刚 ZHAO, Zhenggang
  • 李芳红 LI, Fanghong
Agents
  • 南京苏高专利商标事务所(普通合伙) NANJING SUGAO PATENT AND TRADEMARK FIRM (ORDINARY PARTNERSHIP)
Priority Data
201510117994.X17.03.2015CN
201610081270.905.02.2016CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF GENE ENGINEERING BACTERIA VPN 20009-M IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING CANCER METASTASIS
(FR) UTILISATION D'UNE SOUCHE DE BACTÉRIE GÉNÉTIQUEMENT MODIFIÉE, DÉNOMMÉE VPN20009-M, DANS LA PRÉPARATION DE MÉDICAMENTS DESTINÉS À LA PRÉVENTION ET AU TRAITEMENT D'UNE MÉTASTASE D'UN CANCER
(ZH) 基因工程菌VNP20009-M在制备预防和治疗癌症转移的药物上的应用
Abstract
(EN)
Provided is a use of an attenuated gene engineering Salmonella typhimurium strain VPN 20009-M in the preparation of medicaments for preventing and treating cancer metastasis.
(FR)
L'invention concerne une utilisation d'une souche atténuée de Salmonella typhimurium génétiquement modifiée, dénommée VPN 20009-M, dans la préparation de médicaments destinés à la prévention et au traitement d'une métastase d'un cancer.
(ZH)
提供了减毒鼠伤寒沙门氏菌的基因工程菌VNP20009-M在制备预防和治疗转移后癌症的药物上的应用。
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