Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Saturday 31.10.2020 at 7:00 AM CET
Settings

Settings

Goto Application

1. WO2016145039 - ENHANCED FRAGMENTATION AND REPAIR OF NUCLEIC ACIDS

Publication Number WO/2016/145039
Publication Date 15.09.2016
International Application No. PCT/US2016/021503
International Filing Date 09.03.2016
IPC
C12N 15/09 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
CPC
C12N 15/09
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
Applicants
  • RUBICON GENOMICS, INC. [US]/[US]
Inventors
  • LANGMORE, John
  • KAMBEROV, Emmanuel
Agents
  • FIELD, Bret, E.
Priority Data
62/131,01510.03.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ENHANCED FRAGMENTATION AND REPAIR OF NUCLEIC ACIDS
(FR) FRAGMENTATION ET RÉPARATION AMÉLIORÉES D'ACIDES NUCLÉIQUES
Abstract
(EN)
Provided herein are method of simultaneous shearing and end-repair of nucleic acids. In some aspect, proteins that bind to the termini of a nucleic acid may be used in conjunction with hydrodynamic shearing to reduce the shear force required to fragment the nucleic acid.
(FR)
La présente invention concerne un procédé simultané de cisaillement et de réparation terminale d'acides nucléiques. Selon certains aspects, des protéines qui se lient aux terminaisons d'un acide nucléique peuvent être utilisées conjointement avec le cisaillement hydrodynamique afin de réduire la force de cisaillement requise pour fragmenter l'acide nucléique.
Latest bibliographic data on file with the International Bureau