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1. WO2016136925 - COMPOSITION FOR SKIN

Publication Number WO/2016/136925
Publication Date 01.09.2016
International Application No. PCT/JP2016/055749
International Filing Date 26.02.2016
IPC
A61K 8/368 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
368with carboxyl groups directly bound to carbon atoms of aromatic rings
A61K 8/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
34Alcohols
A61K 8/86 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
84obtained by reactions other than those involving only carbon-to-carbon unsaturated bonds
86Polyethers
A61K 31/192 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
192having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 47/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols ; Poloxamers; PEG/POE alkyl ethers
A61K 47/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
CPC
A61K 31/192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
192having aromatic groups, e.g. sulindac, 2-arylpropionic acids, ethacrynic acid
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
A61K 47/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 8/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
34Alcohols
A61K 8/368
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
368with carboxyl groups directly bound to carbon atoms of aromatic rings
A61K 8/86
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
84obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
86Polyethers
Applicants
  • マルホ株式会社 MARUHO CO., LTD. [JP]/[JP]
Inventors
  • 川口 真澄 KAWAGUCHI, Masumi
  • 崎山 祥紀 SAKIYAMA, Hiroki
  • 朴 剛 PAK, Kang
  • 藤田 智之 FUJITA, Tomoyuki
  • 原田 東樹 HARADA, Motoki
  • 與倉 ゆめい YOKURA, Yumei
Agents
  • 特許業務法人みのり特許事務所 MINORI PATENT PROFESSION CORPORATION
Priority Data
2015-03752227.02.2015JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) COMPOSITION FOR SKIN
(FR) COMPOSITION POUR LA PEAU
(JA) 皮膚用組成物
Abstract
(EN)
Provided is an adapalene-containing composition, for skin, not likely to cause any side effects such as dry skin or the like even when used alone. The composition for skin according to the present invention is characterized by comprising (A) adapalene or a salt thereof, and (B) 5-40 wt% of at least one moisturizing component selected from the group consisting of a macrogol having an average molecular weight of 4000 or less, glycerin, and 1,3-butylene glycol. As the moisturizing component, a macrogol having an average molecular weight of 190-1600 and 1,3-butylene glycol are particularly preferable.
(FR)
La présente invention concerne une composition contenant de l'adapalène, pour la peau, qui n'est susceptible de causer aucun effet secondaire tel que la sécheresse cutanée ou similaire même lorsqu'elle est utilisée seule. La composition pour la peau selon la présente invention est caractérisé en ce qu'elle comprend (A) de l'adapalène ou un sel de celui-ci, et (B) de 5 à 40 % en poids d'au moins un composant hydratant choisi dans le groupe constitué d'un macrogol ayant un poids moléculaire moyen de 4000 ou moins, la glycérine, et le 1,3-butylène glycol. En tant que composant hydratant, un macrogol ayant un poids moléculaire moyen de 190 à 1600 et le 1,3-butylène glycol sont particulièrement préférables.
(JA)
 単独で使用しても皮膚乾燥等の副作用が生じにくい、アダパレン含有皮膚用組成物を提供する。 本発明の皮膚用組成物は、(A)アダパレン又はその塩、及び(B)5~40重量%の、平均分子量4000以下のマクロゴール、グリセリン及び1,3-ブチレングリコールからなる群より選択される少なくとも1種の保湿成分、を含むことを特徴とする。前記保湿成分として、特に平均分子量190~1600のマクロゴール及び1,3-ブチレングリコールが好ましい。
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Latest bibliographic data on file with the International Bureau