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10. (WO2016126798) THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/126798    International Application No.:    PCT/US2016/016335
Publication Date: 11.08.2016 International Filing Date: 03.02.2016
IPC:
C07D 401/14 (2006.01), A61P 35/00 (2006.01), A61K 31/53 (2006.01)
Applicants: AGIOS PHARMACEUTICALS, INC. [US/US]; 88 Sidney Street Cambridge, MA 02139 (US)
Inventors: KLUGE, Stefan; (CH)
Agent: RIEGER, Dale, L.; (US)
Priority Data:
62/112,127 04.02.2015 US
Title (EN) THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
(FR) COMPOSÉS THÉRAPEUTIQUEMENT ACTIFS ET LEURS MÉTHODES D'UTILISATION
Abstract: front page image
(EN)Provided are crystalline forms of 2-Methyl-l-[ (4-[ 6-(trifluoromethyl) pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2- yl)amino]propan-2-ol mesylate useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof said compound.
(FR)La présente invention concerne des formes cristallines de 2-Méthyl-l-[(4-[6-(trifluorométhyl) pyridin-2-yl]-6-{[2- (trifluorométhyle)pyridin-4-yl] amino}-1,3,5-triazin-2-yl)amino]propan-2-ol mésylate utiles pour le traitement du cancer et des méthodes de traitement du cancer, comprenant l'administration dudit composé à un sujet qui en a besoin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)