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1. WO2016113415 - PROCESS FOR THE PREPARATION OF RIOCIGUAT ESSENTIALLY FREE FROM GENOTOXIC IMPURITIES

Publication Number WO/2016/113415
Publication Date 21.07.2016
International Application No. PCT/EP2016/050825
International Filing Date 15.01.2016
IPC
C07D 471/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • SANDOZ AG [CH]/[CH]
Inventors
  • STEFINOVIC, Marijan
  • RICHTER, Frank
  • GRIESSER, Ulrich
  • LANGES, Christoph
Agents
  • KLUSCHANZOFF, Harald
Priority Data
15151499.916.01.2015EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR THE PREPARATION OF RIOCIGUAT ESSENTIALLY FREE FROM GENOTOXIC IMPURITIES
(FR) PROCÉDÉ DE PRÉPARATION DE RIOCIGUAT ESSENTIELLEMENT EXEMPT D'IMPURETÉS GÉNOTOXIQUES
Abstract
(EN)
The invention relates to a new process for the purification of riociguat and to new crystalline solvates which are useful intermediates in the purification of riociguat.
(FR)
L'invention concerne un nouveau procédé pour la purification de riociguat et de nouveaux solvates cristallins qui sont des intermédiaires utiles dans la purification de riociguat.
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