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1. (WO2016106403) THERAPEUTIC COMPOSITIONS AND METHODS FOR MALIGNANT TUMORS WITH RNAI MOLECULES TARGETED TO HSP47 AND P21
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/106403    International Application No.:    PCT/US2015/067558
Publication Date: 30.06.2016 International Filing Date: 28.12.2015
Chapter 2 Demand Filed:    20.10.2016    
IPC:
A61K 9/127 (2006.01), A61K 31/7088 (2006.01), A61K 31/713 (2006.01)
Applicants: NITTO DENKO CORPORATION [JP/JP]; 1-2 Shimohozumi 1-chome Ibaraki-shi Osaka 567-8680 (JP).
YING, Wenbin [US/US]; (US) (US only)
Inventors: YING, Wenbin; (US).
YONEDA, Akihiro; (JP).
TAMURA, Yasuaki; (JP).
MINOMI, Kenjirou; (JP).
MAJETI, Bharat; (US).
LIU, Jihua; (US)
Agent: ECKMAN, Richard R.; (US)
Priority Data:
2014-266198 26.12.2014 JP
62/184,195 24.06.2015 US
62/266,670 13.12.2015 US
Title (EN) THERAPEUTIC COMPOSITIONS AND METHODS FOR MALIGNANT TUMORS WITH RNAI MOLECULES TARGETED TO HSP47 AND P21
(FR) COMPOSITIONS THÉRAPEUTIQUES ET MÉTHODES DESTINÉES À TRAITER LES TUMEURS MALIGNES À L'AIDE DE MOLÉCULES D'ARNI CIBLANT HSP47 ET P21
Abstract: front page image
(EN)This invention provides compositions and methods for preventing or treating a malignant tumor in a mammal in need thereof, by administering to the mammal a therapeutically effective amount of a composition comprising RNAi molecules, which RNAi molecules can be active in reducing expression of Hsp47, or a combination of RNAi molecules active for Hsp47 and p21
(FR)Cette invention concerne des compositions et des méthodes destinées à prévenir ou à traiter une tumeur maligne chez un mammifère en ayant besoin, par administration audit mammifère d'une quantité thérapeutiquement efficace d'une composition comprenant des molécules d'ARNi, lesdites molécules d'ARNi pouvant être actives pour réduire l'expression de Hsp47, ou une combinaison de molécules d'ARNi actives pour réduire l'expression de Hsp47 et de p21.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)