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1. (WO2016106387) NUCLEIC ACID APTAMERS TO TREAT HISTONE-INDUCED DISEASE STATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/106387    International Application No.:    PCT/US2015/067516
Publication Date: 30.06.2016 International Filing Date: 22.12.2015
IPC:
C40B 30/04 (2006.01), C40B 10/00 (2006.01), C07H 21/00 (2006.01), A61K 49/12 (2006.01)
Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION [US/US]; 112 N. Capitol Street 6 Gilmore Hall Iowa City, Iowa 52242-5500 (US)
Inventors: GIANGRANDE, Paloma, H.; (US).
URAK, Kevin; (US).
MILLER, Francis; (US)
Agent: VIKSNINS, Ann, S.,; (US)
Priority Data:
62/095,530 22.12.2014 US
Title (EN) NUCLEIC ACID APTAMERS TO TREAT HISTONE-INDUCED DISEASE STATES
(FR) APTAMÈRES D'ACIDE NUCLÉIQUE POUR TRAITER DES ÉTATS PATHOLOGIQUES INDUITS PAR L'HISTONE
Abstract: front page image
(EN)The invention provides RNA aptamers not more than 90 nucleotides in length which target H3 and/or H4 histones with high affinity and specificity, and methods of using these aptamers.
(FR)La présente invention porte sur des aptamères optimisés et sur des procédés d'utilisation de ces aptamères.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)