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1. (WO2016106309) 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/106309    International Application No.:    PCT/US2015/067359
Publication Date: 30.06.2016 International Filing Date: 22.12.2015
IPC:
C07D 403/12 (2006.01), C07D 231/14 (2006.01), C07D 401/12 (2006.01), C07D 403/14 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01), A61P 11/00 (2006.01), A61K 31/415 (2006.01), A61K 31/4439 (2006.01), A61K 31/496 (2006.01), A61K 31/5377 (2006.01), A61K 31/541 (2006.01)
Applicants: AXIKIN PHARMACEUTICALS, INC. [US/US]; 6185 E. Cornerstone Court, Suite 106 San Diego, CA 92121 (US)
Inventors: LY, Tai, Wei; (US)
Agent: RIEGER, Dale, L.; (US)
Priority Data:
62/096,308 23.12.2014 US
Title (EN) 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS
(FR) INHIBITEURS DE 3,5-DIAMINOPYRAZOLE KINASE
Abstract: front page image
(EN)Provided herein are 3,5-diaminopyrazoles, for example, compounds of Formula (I), that are useful for modulating regulated-in-COPD kinase activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a RC kinase-mediated disorder, disease, or condition.
(FR)L'invention concerne des 3,5-diaminopyrazoles, par exemple, des composés de Formule (I) qui sont utiles pour moduler l'activité kinase régulée dans la BPCO, et des compositions pharmaceutiques les contenant. L'invention concerne également des méthodes d'utilisation de ces composés pour traiter, prévenir, ou améliorer un ou plusieurs symptômes d'un trouble, d'une maladie, ou d'une affection à médiation par une RC kinase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)