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Machine translation
1. (WO2016106186) PROPHYLAXIS OF THROMBOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/106186    International Application No.:    PCT/US2015/067028
Publication Date: 30.06.2016 International Filing Date: 21.12.2015
IPC:
A61K 39/395 (2006.01), C07K 16/38 (2006.01), A61P 9/10 (2006.01)
Applicants: TRANSLATIONAL SCIENCES, INC. [US/US]; 1840 Overton Park Avenue Memphis, Tennessee 38112 (US)
Inventors: REED, Guy L.; (US)
Agent: WARREN, William L.; (US)
Priority Data:
62/095,462 22.12.2014 US
Title (EN) PROPHYLAXIS OF THROMBOSIS
(FR) PROPHYLAXIE DE LA THROMBOSE
Abstract: front page image
(EN)The invention provides a method and composition for preventing thrombosis and complications associated therewith by targeting Sf2 directly. The invention provides Sf2-deficiency or prophylactic administration of a therapeutic agent, such as a Sf2 antagonist or a Sf2 antibody, markedly reduces thrombus formation that would otherwise be caused due to surgery, immobility, genetic abnormality, cancer, trauma, or other risk factors.
(FR)La présente invention concerne un procédé et une composition pour la prévention de la thrombose et des complications associées à celle-ci par ciblage direct de Sf2. L'invention porte sur une déficience en Sf2 ou l'administration prophylactique d'un agent thérapeutique, tel qu'un antagoniste Sf2 ou un anticorps Sf2, pour réduire fortement la formation d'un thrombus qui pourrait être provoqué en raison d'une chirurgie, d'une immobilité, d'anomalies génétiques, d'un cancer, d'un traumatisme ou d'autres facteurs de risque.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)