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1. (WO2016106146) METHODS FOR IMMUNOMODULATION OF CANCER AND INFECTIOUS DISEASE THERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/106146    International Application No.:    PCT/US2015/066805
Publication Date: 30.06.2016 International Filing Date: 18.12.2015
IPC:
A01N 55/02 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; Office of Technology Transfer 1111 Franklin Street, 12th Floor Oakland, California 94607 (US)
Inventors: DEGREGORIO, Michael W.; (US)
Agent: HAO, Joe C.; (US)
Priority Data:
62/096,487 23.12.2014 US
Title (EN) METHODS FOR IMMUNOMODULATION OF CANCER AND INFECTIOUS DISEASE THERAPY
(FR) PROCÉDÉS D'IMMUNOMODULATION DE CANCER ET THÉRAPIE DE MALADIE INFECTIEUSE
Abstract: front page image
(EN)The present invention provides methods for modulating the immune response of a subject to a therapeutic agent, the method comprising administering an effective amount of a triphenyl ethylene (TRIP) compound with an effective amount of the therapeutic agent. In particular embodiments, the TRIP compound enhances the immune response of the subject to the therapeutic agent. In some embodiments, the TRIP compound is administered in different dosing schedules to provide a biphasic immunomodulation effect.
(FR)La présente invention concerne des procédés permettant de moduler la réponse immunitaire d'un sujet à un agent thérapeutique, le procédé consistant à administrer une quantité efficace d'un composé triphényléthylène (TRIP) avec une quantité efficace de l'agent thérapeutique. Dans des modes de réalisation particuliers, le composé TRIP améliore la réponse immunitaire du sujet à l'agent thérapeutique. Dans certains modes de réalisation, le composé TRIP est administré selon différents programmes de dosage pour fournir un effet d'immunomodulation biphasique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)