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1. (WO2016103269) POPULATIONS OF NEURAL PROGENITOR CELLS AND METHODS OF PRODUCING AND USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/103269    International Application No.:    PCT/IL2015/051253
Publication Date: 30.06.2016 International Filing Date: 23.12.2015
IPC:
C12N 5/0793 (2010.01), C12N 5/079 (2010.01)
Applicants: RAMOT AT TEL-AVIV UNIVERSITY LTD. [IL/IL]; P.O. Box 39296 6139201 Tel-Aviv (IL)
Inventors: ELKABETZ, Yechiel; (IL).
EDRI, Reuven; (IL).
YAFFE, Yakey; (IL).
MEISSNER, Alexander; (US).
ZILLER, Michael J.; (US)
Agent: EHRLICH, Gal; (IL)
Priority Data:
62/096,184 23.12.2014 US
Title (EN) POPULATIONS OF NEURAL PROGENITOR CELLS AND METHODS OF PRODUCING AND USING SAME
(FR) POPULATIONS DE CELLULES PROGÉNITRICES NEURONALES ET LEURS PROCÉDÉS DE PRODUCTION ET D'UTILISATION
Abstract: front page image
(EN)An isolated population of cells is provided the cells comprise at least 10 % HES5+ cells, wherein said HES5+ cells are: (i) early radial glial (E -RG) cells; (ii) mid radial glial (M-RG) cells; (iii) late radial glial (L-RG) cells; or (iv) long term neural progenitor (LNP) cells. Also provided are additional populations of neural cells and use of the populations and methods of producing same.
(FR)L'invention concerne une population isolée de cellules comprenant au moins 10 % de cellules HES5+, lesdites cellules HES5+ étant (i) des cellules gliales radiales précoces (E-RG), (ii) des cellules gliales radiales intermédiaires (M-RG), (iii) des cellules gliales radiales tardives (L-RG), ou (iv) des cellules progénitrices neuronales à longue durée de vie (LNP). L'invention concerne également des populations supplémentaires de cellules neuronales, l'utilisation de ces populations et leurs procédés de production.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)