WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2016100926) SYNERGISTIC CO-ADMINISTRATION OF COMPUTATIONALLY OPTIMIZED BROADLY REACTIVE ANTIGENS FOR HUMAN AND AVIAN H5N1 INFLUENZA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/100926    International Application No.:    PCT/US2015/066890
Publication Date: 23.06.2016 International Filing Date: 18.12.2015
IPC:
A61K 39/145 (2006.01), C12N 7/01 (2006.01), C12N 15/866 (2006.01)
Applicants: OREGON HEALTH & SCIENCE UNIVERSITY [US/US]; 3181 Southwest Sam Jackson Park Road Portland, OR 97239 (US).
SANOFI PASTEUR, INC. [US/US]; 1 Discovery Drive Swiftwater, PA 18730 (US)
Inventors: ROSS, Ted, Milburn; (US).
ALEFANTIS, Tim; (US).
CARTER, Donald, Martin, Jr.; (US).
DARBY, Christopher, Austin; (US).
KLEANTHOUS, Harold; (US)
Agent: DONALDSON, Timothy B.; (US)
Priority Data:
62/094,795 19.12.2014 US
Title (EN) SYNERGISTIC CO-ADMINISTRATION OF COMPUTATIONALLY OPTIMIZED BROADLY REACTIVE ANTIGENS FOR HUMAN AND AVIAN H5N1 INFLUENZA
(FR) CO-ADMINISTRATION SYNERGIQUE D'ANTIGÈNES RÉACTIFS À LARGE SPECTRE OPTIMISÉS PAR LE CALCUL POUR LA GRIPPE H5N1 HUMAINE ET AVIAIRE
Abstract: front page image
(EN)The present invention provides co-administration (e.g., immunogenic cocktail and/or prime-boost regimens) of computationally optimized H5N 1 influenza hemagglutinin (HA) polypeptides that. Co-administration of the optimized H5N 1 influenza hemagglutinin (HA) polypeptides facilitates synergistic neutralization of viral infection and provides for improved protective immunity (e.g., a broad reactive immune response) to multiple H5N 1 influenza virus clades and strains.
(FR)La présente invention concerne la co-administration (par exemple, cocktail immunogénique et/ou régimes de primo-immunisation/rappel) de polypeptides d'hémagglutinine (HA) de la grippe H5N1 optimisés par le calcul. Cette co-administration des polypeptides d'hémagglutinine (HA) de la grippe H5N1 optimisés facilite la neutralisation synergique d'une infection virale et permet d'améliorer l'immunité protectrice (par exemple, une réponse immunitaire réactive étendue) contre de multiples clades et souches du virus de la grippe H5N1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)