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1. (WO2016100889) CODON OPTIMIZATION FOR TITER AND FIDELITY IMPROVEMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/100889    International Application No.:    PCT/US2015/066823
Publication Date: 23.06.2016 International Filing Date: 18.12.2015
IPC:
C12P 21/02 (2006.01), C12P 19/34 (2006.01), C07K 1/02 (2006.01)
Applicants: SUTRO BIOPHARMA, INC. [US/US]; 310 Utah Avenue, Suite 150 South San Francisco, California 94080 (US)
Inventors: YIN, Gang; (US)
Agent: NG, Jennifer K.; (US)
Priority Data:
62/094,767 19.12.2014 US
Title (EN) CODON OPTIMIZATION FOR TITER AND FIDELITY IMPROVEMENT
(FR) OPTIMISATION DE CODONS EN VUE D'AMÉLIORER LES TITRES ET LA FIDÉLITÉ
Abstract: front page image
(EN)The invention provides methods for producing a protein in a cell free protein synthesis system such that the protein does not contain an asparagine (Asn or N) residue at serine (Ser or S) positions. Also provided are compositions and nucleic acid templates for use in the methods described herein.
(FR)L'invention concerne des procédés pour produire une protéine dans un système de synthèse protéique acellulaire de sorte que ladite protéine ne contient aucun résidu asparagine (Asn ou N) sur des positions sérine (Ser ou S). L'invention concerne également des compositions et des molécules gabarits d'acides nucléiques destinées à être utilisées dans les procédés selon l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)