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1. (WO2016100272) FUNGAL GENOME MODIFICATION SYSTEMS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/100272    International Application No.:    PCT/US2015/065693
Publication Date: 23.06.2016 International Filing Date: 15.12.2015
IPC:
C12N 15/80 (2006.01), C12N 9/22 (2006.01)
Applicants: DANISCO US INC [US/US]; 925 Page Mill Road Palo Alto, California 94304 (US)
Inventors: BOWER, Benjamin S.; (US).
CHAN, Jimmy; (US).
GE, Jing; (US).
GU, Xiaogang; (US).
MADRID, Susan Mampusti; (US).
SONG, Danfeng; (US).
SONG, Mingmin; (US).
WARD, Michael; (US)
Agent: HONG, Mei; (US)
Priority Data:
PCT/CN2014/093914 16.12.2014 CN
PCT/CN2014/093916 16.12.2014 CN
PCT/CN2014/093918 16.12.2014 CN
Title (EN) FUNGAL GENOME MODIFICATION SYSTEMS AND METHODS OF USE
(FR) SYSTÈMES DE MODIFICATION DU GÉNOME DE CHAMPIGNON ET LEURS PROCÉDÉS D’UTILISATION
Abstract: front page image
(EN)Compositions and methods are provided for genome modification at a target site in the genome of a filamentous fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for modifying or altering the target site. Aspects in which the filamentous fungal cell being modified has a defective non-homologous end joining pathway are also provided.
(FR)La présente invention concerne des compositions et des procédés de modification du génome au niveau d'un site cible dans le génome d'une cellule de champignon filamenteux. Les procédés et les compositions sont élaborés pour un système de polynucléotide guide/endonucléase Cas de modification ou d'altération du site cible. Sont également prévus des aspects, dans lesquels la cellule de champignon filamenteux qui est modifiée présente une voie de jonction d'extrémités défectueuse non homologue.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)