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Machine translation
1. (WO2016100050) ERK INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/100050    International Application No.:    PCT/US2015/064860
Publication Date: 23.06.2016 International Filing Date: 10.12.2015
IPC:
C07D 471/04 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
SILIPHAIVANH, Phieng [US/US]; (US) (NZ, US only).
METHOT, Joey [US/US]; (US) (NZ, US only).
LIPFORD, Kathryn Ann [US/US]; (US) (NZ, US only).
MOLINARI, Danielle [US/US]; (US) (NZ, US only).
SLOMAN, David, L. [US/US]; (US) (NZ, US only).
WITTER, David [US/US]; (US) (NZ, US only).
ZHOU, Hua [CN/US]; (US) (NZ, US only).
BOYCE, Christopher [US/US]; (US) (NZ, US only).
HUANG, Xianhai [CN/US]; (US) (NZ, US only).
LIM, Jongwon [KR/US]; (US) (NZ, US only).
GUERIN, David [US/US]; (US) (NZ, US only).
KARUNAKARAN, Ganesh Babu [IN/IN]; (IN) (NZ, US only).
BAKSHI, Raman Kumar [US/IN]; (IN) (NZ, US only).
LIU, Ziping [CA/CN]; (CN) (NZ, US only).
FU, Jianmin [US/CN]; (CN) (NZ, US only).
WAN, Zhilong [CN/CN]; (CN) (NZ, US only).
LIU, Wei [CN/CN]; (CN) (NZ, US only)
Inventors: SILIPHAIVANH, Phieng; (US).
METHOT, Joey; (US).
LIPFORD, Kathryn Ann; (US).
MOLINARI, Danielle; (US).
SLOMAN, David, L.; (US).
WITTER, David; (US).
ZHOU, Hua; (US).
BOYCE, Christopher; (US).
HUANG, Xianhai; (US).
LIM, Jongwon; (US).
GUERIN, David; (US).
KARUNAKARAN, Ganesh Babu; (IN).
BAKSHI, Raman Kumar; (IN).
LIU, Ziping; (CN).
FU, Jianmin; (CN).
WAN, Zhilong; (CN).
LIU, Wei; (CN)
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
PCT/CN2014/093860 15.12.2014 CN
Title (EN) ERK INHIBITORS
(FR) INHIBITEURS D'ERK
Abstract: front page image
(EN)The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.
(FR)La présente invention concerne un composé de Formule (I) ou ses sels, esters, et promédicaments pharmaceutiquement acceptables, qui sont des inhibiteurs d'ERK2. L'invention fournit également une composition pharmaceutique comprenant une quantité efficace d'au moins un composé de Formule (I) et un support pharmaceutiquement acceptable. L'invention fournit également une composition pharmaceutique comprenant une quantité efficace d'au moins un composé de Formule (I) et une quantité efficace d'au moins un autre ingrédient pharmaceutiquement actif (tel que, par exemple, un agent chimiothérapeutique), et un support pharmaceutiquement acceptable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)