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1. (WO2016099835) DERMATOLOGICAL COMPOSITION OF PAPAIN IN GEL FOR THE ATRAUMATIC REMOVAL OF DERMAL NECROSIS AND METHOD OF PREPARING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/099835    International Application No.:    PCT/US2015/062727
Publication Date: 23.06.2016 International Filing Date: 25.11.2015
IPC:
A61K 8/66 (2006.01)
Applicants: BRIX USA, LLC [US/US]; 113 Barksdale Professional Center Newark, Delaware 19711 (US)
Inventors: DOBBOLETTA, Mauricio; (AR)
Agent: MUNCY, Joe, McKinney; Muncy, Geissler, Olds & Lowe, P.C. 4000 Legato Rd., Suite 310 Fairfax, Virginia 22033 (US)
Priority Data:
P 2014 01 04785 19.12.2014 AR
Title (EN) DERMATOLOGICAL COMPOSITION OF PAPAIN IN GEL FOR THE ATRAUMATIC REMOVAL OF DERMAL NECROSIS AND METHOD OF PREPARING SAME
(FR) COMPOSITION DERMATOLOGIQUE À LA PAPAÏNE EN GEL DESTINÉE AU RETRAIT ATRAUMATIQUE DE NÉCROSE DERMIQUE ET PROCÉDÉ DE PRÉPARATION
Abstract: front page image
(EN)A papain dermatological gel composition is disclosed for the atraumatic treatment of dermal necrosis which comprises papain with a final activity of at least 6,000 U/mg, wherein the papain is bio-encapsulated in a mixture of pH=7 buffer / C3-6 polyol / pectin / C2-6 alkanolamine / nonionic emulsifier, together with pharmaceutically acceptable dyeing agents, preservatives and solvents.
(FR)La présente invention concerne une composition de gel dermatologique à la papaïne destinée au traitement atraumatique de nécrose dermique, comprenant de la papaïne ayant une activité finale d’au moins 6 000 U/mg, la papaïne étant bio-encapsulée dans un mélange de tampon de pH=7/polyol en C3-6/pectine/alcanolamine en C2-6/émulsifiant non ionique, conjointement avec des agents colorants, conservateurs et solvants pharmaceutiquement acceptables.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)