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1. (WO2016099452) RAS-INHIBITING INDENYL ACETAMIDE COMPOUNDS, COMPOSITIONS, AND USES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/099452    International Application No.:    PCT/US2014/070511
Publication Date: 23.06.2016 International Filing Date: 16.12.2014
Chapter 2 Demand Filed:    10.10.2016    
IPC:
A61K 31/165 (2006.01)
Applicants: ADT PHARMACEUTICALS, INC. [US/US]; 31691 Shoal Water Dr. Orange Beach, Alabama 36561 (US)
Inventors: PIAZZA, Gary A.; (US).
CHEN, Xi; (US).
KEETON, Adam B.; (US)
Agent: PILLAI, Xavier; (US)
Priority Data:
Title (EN) RAS-INHIBITING INDENYL ACETAMIDE COMPOUNDS, COMPOSITIONS, AND USES
(FR) COMPOSÉS D'ACÉTAMIDE INDÉNYLE INHIBITEUR DE RAS, COMPOSITIONS ET UTILISATIONS
Abstract: front page image
(EN)Disclosed are compounds, for example, compounds of formula (I), wherein R, R0 R1-R8, n, X, Y, Y1, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
(FR)La présente invention concerne des composés, par exemple des composés de formule (I), dans laquelle R, R0 R1-R8, n, X, Y, Y1 et E sont tels que décrits ici, des compositions pharmaceutiques contenant ces composés, et des méthodes de traitement ou de prévention d'une maladie ou d'une affection, par exemple le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)