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1. (WO2016097995) ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/097995    International Application No.:    PCT/IB2015/059631
Publication Date: 23.06.2016 International Filing Date: 15.12.2015
IPC:
C07D 413/06 (2006.01), A61K 31/42 (2006.01), C07D 413/12 (2006.01), C07D 261/08 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH)
Inventors: FU, Jiping; (US).
JIN, Xianming; (US).
KARUR, Subramanian; (US).
LAPOINTE, Guillaume; (US).
MADERA, Ann Marie; (US).
SWEENEY, Zachary Kevin; (US)
Common
Representative:
NOVARTIS AG; Lichtstrasse 35 CH-4056 Basel (CH)
Priority Data:
62/092,402 16.12.2014 US
Title (EN) ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS
(FR) COMPOSÉS D'ACIDES D'ISOXAZOLE EN TANT QU'INHIBITEURS DE LPXC
Abstract: front page image
(EN)This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for treating infections caused by Gram-negative bacteria.
(FR)Cette invention se rapporte, de manière générale, à des composés de formule I et à des compositions contenant de tels composés, ainsi qu'à des procédés d'utilisation de tels composés pour traiter les infections bactériennes. Selon certains aspects, l'invention concerne des méthodes et des compositions pouvant être utilisées pour le traitement d'infections provoquées par des bactéries gram-négatives.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)