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Pub. No.:    WO/2016/097759    International Application No.:    PCT/GB2015/054078
Publication Date: 23.06.2016 International Filing Date: 18.12.2015
A61K 31/00 (2006.01), A61K 31/122 (2006.01), A61K 31/4184 (2006.01), A61K 31/4985 (2006.01), A61P 33/10 (2006.01)
Applicants: ABERYSTWYTH UNIVERSITY [GB/GB]; Penglais Campus Aberystwyth Ceredigion SY23 3FL (GB)
Inventors: HOFFMANN, Karl Francis; (GB).
NASH, Robert James; (GB).
PEAK, Emily; (GB)
Agent: MYATT, James; Appleyard Lees IP LLP 15 Clare Road Halifax HX1 2HY (GB)
Priority Data:
1422846.4 19.12.2014 GB
Abstract: front page image
(EN)The present invention relates to compounds, in particular derivatives of the diterpenoids sempervirol and 7‐keto‐sempervirol, and their use in therapy, including in pharmaceutical compositions and combinations, especially in the treatment and/or prophylaxis of the tropical diseases schistosomiasis and/or fascioliasis, for example in humans or in non‐human land mammals such as sheep, cattle, other ruminants, or goats.
(FR)La présente invention concerne des composés, en particulier des dérivés de diperténoïdes du type sempervirol et 7‐céto ‐ sempervirol, et leur utilisation en thérapie, notamment dans des compositions pharmaceutiques et des combinaisons, en particulier dans le traitement et/ou la prophylaxie de maladies tropicales telles que la schistosomiase et/ou la fascioliase, par exemple chez les humains ou des mammifères terrestres non humains comme les moutons, les bovins, d'autres ruminants ou les caprins.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)