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1. (WO2016097317) INTRA-OPERATIVE IMAGING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/097317    International Application No.:    PCT/EP2015/080545
Publication Date: 23.06.2016 International Filing Date: 18.12.2015
IPC:
A61K 49/00 (2006.01)
Applicants: BRACCO IMAGING SPA [IT/IT]; Via Egidio Folli, 50 20134 Milano (IT)
Inventors: MAIOCCHI, Alessandro; (IT).
BRIOSCHI, Chiara; (IT).
VALBUSA, Giovanni; (IT).
UGGERI, Fulvio; (IT)
Agent: RAVIZZA, Claudio; (IT)
Priority Data:
EP14199240.4 19.12.2014 EP
Title (EN) INTRA-OPERATIVE IMAGING
(FR) IMAGERIE INTRA-OPÉRATOIRE
Abstract: front page image
(EN)The present invention relates to the use of a NIR fluorescent probe comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety in the fluorescence- guided surgery of pathologic regions and to an optical imaging method that comprises using this fluorescent probe for the identification and demarcation of tumor margins during the surgical resection.
(FR)La présente invention porte sur l'utilisation d'une sonde fluorescente IRP comprenant un peptide cyclique à base d'aza-bicycloalcane marqué avec une partie colorant Cy5.5 dans le domaine de la chirurgie guidée par fluorescence de régions pathologiques, et sur un procédé d'imagerie optique qui comprend l'utilisation de cette sonde fluorescente pour l'identification et la démarcation de marges tumorales pendant la résection chirurgicale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)