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1. (WO2016097305) NOVEL METHOD FOR THE DETECTION OF PGLU-ABETA PEPTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/097305    International Application No.:    PCT/EP2015/080518
Publication Date: 23.06.2016 International Filing Date: 18.12.2015
IPC:
G01N 33/68 (2006.01)
Applicants: PROBIODRUG AG [DE/DE]; Weinbergweg 22 06120 Halle (Saale) (DE)
Inventors: KLEINSCHMIDT, Martin; (DE).
HOFFMANN, Torsten; (DE).
RAHFELD, Jens-Ulrich; (DE).
SCHILLING, Stephan; (DE).
PUNNAMOOTTIL, Beena; (DE).
ADLER, Michael; (DE)
Agent: MAIKOWSKI & NINNEMANN; Post Box 15 09 20 10671 Berlin (DE)
Priority Data:
62/094,500 19.12.2014 US
Title (EN) NOVEL METHOD FOR THE DETECTION OF PGLU-ABETA PEPTIDES
(FR) NOUVEAU PROCÉDÉ PERMETTANT LA DÉTECTION DE PEPTIDES PGLU-ABÊTA
Abstract: front page image
(EN)The invention relates to a highly sensitive method for the detection of pGlu-Abeta (pGlu-Αβ) peptides and the use of this method in the diagnosis of neurodegenerative diseases, such as Alzheimer's disease and Mild Cognitive Impairment. The invention further concerns a novel method for monitoring the effectiveness of a treatment of neurodegenerative diseases by monitoring changes in the level of pGlu-Αβ peptides.
(FR)L'invention concerne un procédé hautement sensible permettant la détection de peptides pGlu-Abêta (pGlu-Αβ), et l'utilisation de ce procédé dans le diagnostic de maladies neurodégénératives telles que la maladie d'Alzheimer et un trouble cognitif léger. L'invention concerne en outre un nouveau procédé pour surveiller l'efficacité d'un traitement de maladies neurodégénératives par surveillance de changements du niveau de peptides pGlu-Αβ.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)