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1. (WO2016095805) PYRROLOPYRIMIDINE COMPOUND
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/095805    International Application No.:    PCT/CN2015/097411
Publication Date: 23.06.2016 International Filing Date: 15.12.2015
IPC:
C07D 487/04 (2006.01), A61K 31/519 (2006.01), A61K 31/5377 (2006.01), A61P 35/00 (2006.01)
Applicants: CENTAURUS BIOPHARMA CO., LTD. [CN/CN]; No.16 Building, No.3 Minzhuang Road, Haidian District Beijing 100195 (CN).
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD [CN/CN]; No.369 Yuzhou South Rd., Haizhou District Lianyungang, Jiangsu 222062 (CN).
LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. [CN/CN]; No. 16 Jinqiao Road, Dapu Industry Park, Lianyungang Economy and Technology Development Zone Lianyungang City, Jiangsu 222069 (CN)
Inventors: ZHU, Li; (CN).
XIAO, Dengming; (CN).
HU, Yuandong; (CN).
DAI, Liguang; (CN).
DUAN, Xiaowei; (CN).
SUN, Yinghui; (CN).
PENG, Yong; (CN).
KONG, Fansheng; (CN).
LUO, Hong; (CN).
HAN, Yongxin; (CN).
YANG, Ling; (CN).
WANG, Shanchun; (CN)
Agent: INSIGHT INTELLECTUAL PROPERTY LIMITED; Suite 19A, Tower A, InDo Building, No. 48A Zhichun Road, Haidian District Beijing 100098 (CN)
Priority Data:
201410784461.2 16.12.2014 CN
Title (EN) PYRROLOPYRIMIDINE COMPOUND
(FR) COMPOSÉ DE PYRROLOPYRIMIDINE
(ZH) 吡咯并嘧啶化合物
Abstract: front page image
(EN)The present application relates to the field of pharmaceutical chemistry, and in particular, to a pyrrolopyrimidine compound represented by general formula (I), a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The present invention further relates to a method for preparing the pyrrolopyrimidine compound represented by general formula (I), pharmaceutical compositions and an application of the pyrrolopyrimidine compound in treating diseases mediated by Janus Kinase.
(FR)La présente invention concerne le domaine de la chimie pharmaceutique, et en particulier, un composé de pyrrolopyrimidine représenté par la formule générale (I), un stéréoisomère de celui-ci, ou un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne en outre un procédé de préparation du composé de pyrrolopyrimidine représenté par la formule générale (I), des compositions pharmaceutiques et une application du composé de pyrrolopyrimidine dans le traitement de maladies médiées par la Janus kinase.
(ZH)本申请涉及药物化学领域,具体涉及如式I所示的吡咯并嘧啶化合物、其立体异构体、其药学上可接受的盐。本申请还涉及制备如式I所示的吡咯并嘧啶化合物的方法、药物组合物、以及该化合物在治疗两面神激酶介导的疾病中的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)