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1. (WO2016094273) METHODS FOR UPREGULATING IMMUNE RESPONSES USING COMBINATIONS OF ANTI-RGMB AND ANTI-PD-1 AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/094273    International Application No.:    PCT/US2015/064203
Publication Date: 16.06.2016 International Filing Date: 07.12.2015
IPC:
A61K 39/395 (2006.01), A61P 37/02 (2006.01), G01N 33/53 (2006.01)
Applicants: DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 450 Brookline Avenue Boston, MA 02215-5450 (US)
Inventors: FREEMAN, Gordon, J.; (US).
XIAO, Yanping; (US)
Agent: SMITH, DeAnn, F.; (US)
Priority Data:
62/088,855 08.12.2014 US
Title (EN) METHODS FOR UPREGULATING IMMUNE RESPONSES USING COMBINATIONS OF ANTI-RGMB AND ANTI-PD-1 AGENTS
(FR) PROCÉDÉS DE RÉGULATION À LA HAUSSE DES RÉPONSES IMMUNITAIRES À L'AIDE DE COMBINAISONS D'AGENTS ANTI-RGMB ET D'AGENTS ANTI-PD-1
Abstract: front page image
(EN)The present invention relates to methods for upregulating immune responses using combinations of anti-RGMb and anti-PD-1 agents.
(FR)La présente invention concerne des procédés destinés à réguler à la hausse des réponses immunitaires à l'aide de combinaisons d'agents anti-RGMb et anti-PD -1.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)