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Machine translation
1. (WO2016093205) METHOD FOR PRODUCING CATIONIC LIPID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/093205    International Application No.:    PCT/JP2015/084345
Publication Date: 16.06.2016 International Filing Date: 08.12.2015
IPC:
C07C 213/08 (2006.01), C07C 219/06 (2006.01)
Applicants: NOF CORPORATION [JP/JP]; 20-3, Ebisu 4-chome, Shibuya-ku, Tokyo 1506019 (JP)
Inventors: OTA Masaki; (JP).
HAMURA Ken; (JP)
Agent: SHIN-EI PATENT FIRM, P.C.; Toranomon East Bldg. 8F, 7-13, Nishi-Shimbashi 1-chome, Minato-ku, Tokyo 1050003 (JP)
Priority Data:
2014-247723 08.12.2014 JP
Title (EN) METHOD FOR PRODUCING CATIONIC LIPID
(FR) PROCÉDÉ DE PRODUCTION DE LIPIDE CATIONIQUE
(JA) カチオン性脂質の製造方法
Abstract: front page image
(EN)Provided is an industrial method for producing a cationic lipid with which it is possible to efficiently obtain a high-purity cationic lipid without requiring special equipment. A cationic lipid represented by formula (1) and a tetraalkylammonium salt having X- are mixed in an organic solvent, tetraalkylammonium iodide is precipitated by concentrating the filtrate obtained by filtering out the precipitated tetraalkylammonium iodide, and a cationic lipid represented by formula (2) is obtained.
(FR)L'invention concerne un procédé industriel de production d'un lipide cationique grâce auquel il est possible d'obtenir de manière efficace un lipide cationique de grande pureté sans nécessité d'équipement spécial. Un lipide cationique représenté par la formule (1) et un sel de tétraalkylammonium ayant X- sont mélangés dans un solvant organique, l'iodure de tétraalkylammonium est précipité par concentration du filtrat obtenu en éliminant par filtration l'iodure de tétraalkylammonium précipité, et un lipide cationique représenté par la formule (2) est obtenu.
(JA) 特殊な設備を必要とせず、高純度なカチオン性脂質を効率的に得ることができる、工業的なカチオン性脂質の製造方法を提供する。下記式(1)で表されるカチオン性脂質と、Xを有するテトラアルキルアンモニウム塩とを有機溶媒中で混合し、析出したヨウ化テトラアルキルアンモニウムをろ別したろ液を濃縮することでヨウ化テトラアルキルアンモニウムを析出させ、下記式(2)で表されるカチオン性脂質を得る。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)