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1. (WO2016091235) 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/091235    International Application No.:    PCT/CZ2015/050005
Publication Date: 16.06.2016 International Filing Date: 14.09.2015
IPC:
A61K 8/60 (2006.01), A61Q 17/04 (2006.01), A61Q 19/08 (2006.01), A61K 31/7076 (2006.01), C07H 19/173 (2006.01), C07H 19/19 (2006.01)
Applicants: UNIVERZITA PALACKEHO V OLOMOUCI [CZ/CZ]; Krizkovskeho 8 771 47 Olomouc (CZ)
Inventors: DOLEZAL, Karel; (CZ).
PLIHALOVA, Lucie; (CZ).
VYLICILOVA, Hana; (CZ).
ZATLOUKAL, Marek; (CZ).
PLIHAL, Ondrej; (CZ).
VOLLER, Jiri; (CZ).
STRNAD, Miroslav; (CZ).
BRYKSOVA, Magdalena; (CZ).
VOSTALOVA, Jitka; (CZ).
RAJNOCHOVA SVOBODOVA, Alena; (CZ).
ULRICHOVA, Jitka; (CZ).
SPICHAL, Lukas; (CZ)
Agent: HARTVICHOVA, Katerina; (CZ)
Priority Data:
PV2014-875 09.12.2014 CZ
Title (EN) 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF
(FR) 6-ARYL-9-GLYCOSYLPURINES ET UTILISATION DE CELLES-CI
Abstract: front page image
(EN)The present invention provides 6-aryl-9-glycosidpurines of general formula I and pharmaceutically acceptable salts thereof with alkali metals, ammonia, amines, or addition salts with acids, wherein Gly represents β-D-arabinofuranosyl or β-D-2´-deoxyribofuranosyl, Ar represents benzyl or furfuryl, each of which can be unsubstituted or substituted by one or more, preferably one to three, substituents selected from the group comprising hydroxyl, alkyl, halogen, alkoxy, amino, mercapto, carboxyl, cyano, amido, sulfo, sulfamido, acyl, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, trifluoromethyl, trifluoromethoxy, for use as antisenescent and UV protective compounds in animals.
(FR)La présente invention concerne les 6-aryl-9-glycosylpurines de formule générale I et des sels pharmaceutiquement acceptables de celles-ci avec des métaux alcalins, l'ammoniac, des amines, ou des sels d'addition avec des acides, où Gly représente β-D-arabinofuranosyle ou β-D-2'-désoxyribofuranosyle, Ar représente benzyle ou furfuryle, chacun pouvant être non substitué ou substitué par un ou plusieurs, de préférence un à trois, substituants choisis dans le groupe comprenant hydroxyle, alkyle, halogène, alcoxy, amino, mercapto, carboxyle, cyano, amido, sulfo, sulfamido, acyle, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, trifluorométhyle, trifluorométhoxy, à utiliser comme composés luttant contre le vieillissement et protégeant des UV chez l'animal.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)