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1. (WO2016089304) USE OF TETRAHYDROPYRIDINES IN THE TREATMENT OF SODIUM CHANNEL RELATED DISEASE AND DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/089304    International Application No.:    PCT/SG2015/050461
Publication Date: 09.06.2016 International Filing Date: 19.11.2015
IPC:
A61K 31/4458 (2006.01), C07D 211/70 (2006.01), A61P 13/00 (2006.01), A61P 21/00 (2006.01), A61P 25/00 (2006.01), A61P 37/00 (2006.01)
Applicants: CENNERV PHARMA (S) PTE. LTD. [SG/SG]; 600 North Bridge Road #05-01 Parkview Square Singapore 188778 (SG)
Inventors: RATTY, Anil Kumar; (SG).
MICHAEL, Entzeroth; (SG)
Agent: YUSARN, Audrey; 24 Raffles Place #27-01 Clifford Centre Singapore 048621 (SG)
Priority Data:
10201408115S 05.12.2014 SG
Title (EN) USE OF TETRAHYDROPYRIDINES IN THE TREATMENT OF SODIUM CHANNEL RELATED DISEASE AND DISORDERS
(FR) UTILISATION DE TÉTRAHYDROPYRIDINES DANS LE TRAITEMENT DE MALADIES ET DE TROUBLES LIÉS AU CANAL SODIQUE
Abstract: front page image
(EN)The present invention provides a method of treating one or more sodium channel related diseases or disorders in an individual, including related symptoms. The method comprises administering to the individual a tetrahydropyridine derivative in an amount effective to treat sodium channel related diseases or disorders in individuals. These compounds are generally categorised as Ritalin related compounds. The present invention also provides compounds for use in the treatment of and also for use in the manufacture of a medicament for the treatment of sodium channel related diseases or disorders in an individual. A method is further provided for the preparation and isolation of the derivatives of the compound of the present invention.
(FR)La présente invention concerne un procédé de traitement d'une ou de plusieurs maladies ou de troubles associés au canal sodique chez un individu, y compris les symptômes associés. Le procédé consiste à administrer au sujet un dérivé de tétrahydropyridine dans une quantité efficace pour traiter des maladies ou des troubles liés au canal sodique chez des individus. Ces composés sont généralement classés comme des composés associés à la Ritaline. La présente invention concerne également des composés destinés à être utilisés dans le traitement de ainsi que dans la fabrication d'un médicament pour le traitement de maladies ou de troubles associés aux canaux sodiques chez un individu. L'invention concerne également un procédé de préparation et d'isolation des dérivés du composé de la présente invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)