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Machine translation
1. (WO2016088903) HETEROCYCLIC COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/088903    International Application No.:    PCT/JP2015/084734
Publication Date: 09.06.2016 International Filing Date: 04.12.2015
IPC:
C07D 401/12 (2006.01), C07D 471/04 (2006.01), C07D 209/02 (2006.01), A61K 31/403 (2006.01), A61K 31/407 (2006.01), A61P 29/00 (2006.01)
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP)
Inventors: DESHPANDE, Anil M.; (IN).
BARAWKAR, Dinesh; (IN).
PATIL, Santosh; (IN).
BANKAR, Digambar; (IN)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
3555/DEL/2014 05.12.2014 IN
Title (EN) HETEROCYCLIC COMPOUNDS
(FR) COMPOSÉS HÉTÉROCYCLIQUES
Abstract: front page image
(EN)The present invention provides a compound represented by the formula (1) : wherein each symbol is as defined in the specification, or a salt thereof has an EP4 receptor antagonistic action, and is useful as an agent for the prophylaxis or treatment of EP4 receptor associated diseases (e.g., rheumatoid arthritis, aortic aneurysm, endometriosis, ankylosing spondylitis etc.) and the like.
(FR)La présente invention concerne un composé représenté par la formule (1) : dans laquelle chaque symbole est tel que défini dans la description, ou un sel de celui-ci qui a une action antagoniste vis-à-vis du récepteur EP4, et qui est utile comme agent pour la prophylaxie ou le traitement de maladies associées au récepteur EP4 (par exemple, la polyarthrite rhumatoïde, l'anévrisme de l'aorte, l'endométriose, la spondylarthrite ankylosante, le cancer du sein inflammatoire etc.) et similaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)