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1. (WO2016088082) AMIDOMETHYL-BIARYL DERIVATIVES COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/088082    International Application No.:    PCT/IB2015/059334
Publication Date: 09.06.2016 International Filing Date: 03.12.2015
IPC:
C07D 213/81 (2006.01), C07C 311/21 (2006.01), C07C 229/06 (2006.01), C07C 233/75 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BELANGER, David [US/US]; (US) (US only).
FLOHR, Stefanie [DE/DE]; (CH) (US only).
GELIN, Christine Fang [US/US]; (US) (US only).
JENDZA, Keith [US/US]; (US) (US only).
JI, Nan [US/US]; (US) (US only).
KARKI, Rajeshri Ganesh [US/US]; (US) (US only).
LIU, Donglei [CN/US]; (US) (US only).
LORTHIOIS, Edwige Liliane Jeanne [FR/FR]; (CH) (US only).
MAINOLFI, Nello [IT/US]; (US) (US only).
POWERS, James J. [US/US]; (US) (US only).
VULPETTI, Anna [IT/CH]; (CH) (US only)
Inventors: BELANGER, David; (US).
FLOHR, Stefanie; (CH).
GELIN, Christine Fang; (US).
JENDZA, Keith; (US).
JI, Nan; (US).
KARKI, Rajeshri Ganesh; (US).
LIU, Donglei; (US).
LORTHIOIS, Edwige Liliane Jeanne; (CH).
MAINOLFI, Nello; (US).
POWERS, James J.; (US).
VULPETTI, Anna; (CH)
Common
Representative:
NOVARTIS AG; Lichtstrasse 35 CH-4056 Basel (CH)
Priority Data:
62/088,091 05.12.2014 US
Title (EN) AMIDOMETHYL-BIARYL DERIVATIVES COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF
(FR) DÉRIVÉS D'AMINOMÉTHYL-BIARYLE EN TANT QU'INHIBITEURS DU FACTEUR D DU COMPLÉMENT ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention provides a compound of formula (I): (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
(FR)La présente invention concerne un composé de formule I : (I) un procédé de fabrication du composés selon l'invention, et son utilisation thérapeutique. La présente invention concerne en outre une combinaison de principes pharmacologiquement actifs et d'une composition pharmaceutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)