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1. (WO2016087932) MACROMOLECULAR TRANSITION METAL COMPLEXES FOR TREATMENT OF CANCER AND PROCESS FOR THEIR PREPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/087932    International Application No.:    PCT/IB2015/002312
Publication Date: 09.06.2016 International Filing Date: 07.12.2015
Chapter 2 Demand Filed:    05.10.2016    
IPC:
C07F 9/50 (2006.01), C07F 15/00 (2006.01), C07F 15/02 (2006.01), C07D 213/22 (2006.01), C08G 63/08 (2006.01), A61P 35/00 (2006.01), A61K 31/295 (2006.01)
Applicants: FACULDADE DE CIÉNCIAS DA UNIVERSIDADE DE LISBOA [PT/PT]; Campo Grande, Edifício C5 1749-016 Lisboa (PT)
Inventors: ANSELMO VIEGAS GARCIA, Maria Helena; (PT).
MARQUES VALENTE, Andreia; (PT).
FERREIRA MORAIS, Tânia Sofia; (PT).
ANTUNES TOMAZ DINIZ, Ana Isabel; (PT)
Agent: GARCIA, Teresa; Soldados da India, 72 1400-340 Lisboa (PT)
Priority Data:
108082 06.12.2014 PT
Title (EN) MACROMOLECULAR TRANSITION METAL COMPLEXES FOR TREATMENT OF CANCER AND PROCESS FOR THEIR PREPARATION
(FR) COMPLEXES DE MÉTAL DE TRANSITION MACROMOLÉCULAIRES POUR LE TRAITEMENT DU CANCER ET LEUR PROCÉDÉ DE PRÉPARATION
Abstract: front page image
(EN)The present invention relates to macromolecular transition metal complexes, characterized by having the general formula (I), to the process for their preparation, and to bidentate and monodentate macroligands. The invention also refers to pharmaceutical compositions and medicaments containing said macromolecular transition metal complexes, and to the use of said pharmaceutical compositions, medicaments and macromolecular transition metal complexes for cancer therapy and/or cancer prevention, as antitumor agent in solid tumors, liquid tumors and/or metastases and/or as radiosensitizer agents.
(FR)La présente invention concerne des complexes de métal de transition macromoléculaires, caractérisés par la formule générale (I), leur procédé de préparation, et des macroligands de monodentates et de bidentates. L'invention concerne également des compositions pharmaceutiques et des médicaments contenant ces complexes de métal de transition macromoléculaires, et l'utilisation desdites compositions pharmaceutiques, des médicaments et des complexes de métal de transition macromoléculaires pour le traitement du cancer et/ou la prévention du cancer, en tant qu'agent antitumoral pour les tumeurs solides, les tumeurs liquides et/ou les métastases et/ou les agents radiosensibilisateurs.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)