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1. (WO2016087457) STABLE LIQUID VACCINIA VIRUS FORMULATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/087457    International Application No.:    PCT/EP2015/078239
Publication Date: 09.06.2016 International Filing Date: 01.12.2015
IPC:
A61K 39/275 (2006.01), A61K 9/08 (2006.01)
Applicants: TRANSGENE SA [FR/FR]; Parc d'innovation Boulevard Gonthier d'Andernach 67400 Illkirch Graffenstaden (FR)
Inventors: CHASLE, Mélina; (FR)
Agent: REGIMBEAU; 20, rue de Chazelles 75847 Paris Cedex 17 (FR)
Priority Data:
14306930.0 01.12.2014 EP
Title (EN) STABLE LIQUID VACCINIA VIRUS FORMULATIONS
(FR) FORMULATIONS LIQUIDES STABLES DE VIRUS DE LA VACCINE
Abstract: front page image
(EN)The present invention relates to liquid formulations of poxvirus, in particular vaccinia virus, stable during storage. Such stable liquid formulations comprise a) a poxvirus, preferably a vaccinia virus, b) a pharmaceutically acceptable buffer, c) a monovalent salt, d) a pharmaceutically acceptable disaccharide or sugar alcohol, and e) a pharmaceutically acceptable chelating agent, wherein the pH of the formulation is comprised between 6.5 and 8.5.
(FR)La présente invention concerne des formulations liquides de poxvirus, en particulier de virus de la vaccine, stables pendant le stockage. Ces formulations liquides stables comprennent a) un poxvirus, de préférence un virus de la vaccine, b) un tampon pharmaceutiquement acceptable, c) un sel monovalent, d) un disaccharide ou un polyol pharmaceutiquement acceptable et e) un agent chélatant pharmaceutiquement acceptable, le pH de la formulation étant compris entre 6,5 et 8,5.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)