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Machine translation
1. (WO2016086813) GPC3 AND ASGPR1 DOUBLE-TARGETED TRANSGENIC IMMUNE EFFECTOR CELL AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/086813    International Application No.:    PCT/CN2015/095938
Publication Date: 09.06.2016 International Filing Date: 30.11.2015
IPC:
C12N 5/10 (2006.01), C12N 15/63 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01)
Applicants: CARSGEN THERAPEUTICS LTD [CN/CN]; 4F, Building 3, No. 466 Yindu Rd, Xuhui District Shanghai 200231 (CN)
Inventors: WANG, Huamao; (CN).
CAI, Xiumei; (CN).
ZHAO, Hongxia; (CN).
SONG, Bo; (CN).
CHEN, Yuanmei; (CN).
ZHU, Yinyu; (CN)
Agent: SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC; 435 Guiping Road Shanghai 200233 (CN)
Priority Data:
201410736009.9 04.12.2014 CN
Title (EN) GPC3 AND ASGPR1 DOUBLE-TARGETED TRANSGENIC IMMUNE EFFECTOR CELL AND USE THEREOF
(FR) CELLULE EFFECTRICE IMMUNE TRANSGÉNIQUE À DOUBLE CIBLE GPC3 ET ASGPR1 ET SON UTILISATION
(ZH) 双靶向GPC3和ASGPR1的转基因免疫效应细胞及其应用
Abstract: front page image
(EN)Provided are a GPC3 and ASGPR1 double-targeted transgenic immune effector cell and a use thereof. The cell is an immune effector cell capable of identifying the gene modifications of GPC3 and ASGPR1 simultaneously, and the cell can be used in the treatment of GPC3 and ASGPR1 double positive tumours, such as liver cancer.
(FR)Cette invention concerne une cellule effectrice immune transgénique à double cible GPC3 et ASGPR1 et son utilisation. La cellule est une cellule effectrice immune capable d'identifier les modifications géniques de GPC3 et ASGPR1 simultanément, la cellule pouvant être utilisée dans le traitement des tumeurs doublement positives à GPC3 et ASGPR1, telles que le cancer du foie.
(ZH)提供了一种双靶向GPC3和ASGPR1的转基因免疫效应细胞及其应用,该细胞是一种能同时识别GPC3和ASGPR1的基因修饰的免疫效应细胞,其可应用于GPC3和ASGPR1双阳性肿瘤如肝癌的治疗。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)